Evidence map›Paper›PMID 35369453›Full record

ArticleFrontiers in microbiology2022

Dihydropyrimidinones Against Multiresistant Bacteria.

Marisa Castro Jara, Allison Carlos Assunção Silva, Marina Ritter, Adriana Fernandes da Silva, Carolina Lambrecht Gonçalves, Pedro Rassier Dos Santos, Luciano Sisconetto Borja, Cláudio Martin Pereira de Pereira, Patrícia da Silva Nascente

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Targeting Breast Cancer: Novel Dihydropyrimidinones As Potent Eg5 Inhibitors.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marisa Castro JaraPostgraduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas, Pelotas, Brazil.
Allison Carlos Assunção SilvaLipidomics and Bioorganics Laboratory, Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Pelotas, Brazil.
Marina RitterLipidomics and Bioorganics Laboratory, Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Pelotas, Brazil.
Adriana Fernandes da SilvaCell Culture and Molecular Biology Laboratory, Federal University of Pelotas, Pelotas, Brazil.
Carolina Lambrecht GonçalvesDepartment of Microbiology and Parasitology, Institute of Biology, Federal University of Pelotas, Pelotas, Brazil.
Pedro Rassier Dos SantosDepartment of Microbiology and Parasitology, Institute of Biology, Federal University of Pelotas, Pelotas, Brazil.
Luciano Sisconetto BorjaLipidomics and Bioorganics Laboratory, Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Pelotas, Brazil.
Cláudio Martin Pereira de PereiraLipidomics and Bioorganics Laboratory, Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Pelotas, Brazil.
Patrícia da Silva NascentePostgraduate Program in Biochemistry and Bioprospecting, Federal University of Pelotas, Pelotas, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in bacterial resistance to antimicrobials has led to high morbidity and mortality rates, posing a major public health problem, requiring the discovery of novel antimicrobial substances. The biological samples were identified as the Gram-negative bacilli

Indexed as

antibacterial activitybiginelli compoundscytotoxicityDHPMdihydropyrimidinoneshospital infection

Identifiers

PMID35369453
PMCPMC8973396

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.