Evidence map›Paper›PMID 35369437›Full record

ArticleFrontiers in microbiology2022

Mutations and Phylogenetic Analyses of SARS-CoV-2 Among Imported COVID-19 From Abroad in Nanjing, China.

Ning Zhao, Nan Zhou, Huafeng Fan, Jie Ding, Xingyu Xu, Xiaoqing Dong, Xiaoxiao Dong, Dandan Xu, Xiaoyu Min, Yan Yu and 3 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. COVID-19, the disease that changed the world.Medicine and pharmacy reports · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ning ZhaoMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Nan ZhouMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Huafeng FanMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Jie DingMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Xingyu XuHangzhou Baocheng Biotechnology Co., Ltd., Hangzhou, China.
Xiaoqing DongMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Xiaoxiao DongMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Dandan XuMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Xiaoyu MinMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Yan YuMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Hongjin GongMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.
Lingfeng MaoHangzhou Baocheng Biotechnology Co., Ltd., Hangzhou, China.
Min HeMicrobiology Laboratory, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a pandemic and is threatening human health globally. The rapid genome sequencing and bioinformatic analysis of SARS-CoV-2 have become a helpful tool in the battle against the COVID-19. Here, we report the genetic characteristics, variations and phylogenetic analysis of SARS-CoV-2 sequenced from 42 clinical specimens. The complete genomes sequencing of SARS-CoV-2 were performed using Oxford Nanopore sequencing. All genomes accumulated mutations compared to the Wuhan-Hu-1 (GenBank Accession No: MN908947.3). Our data of the 42 whole genomes revealed 16 different lineages. The B.1.1 lineage was the most frequent, and 5, 2, 2, 3, and 1 sequences were classified as lineages of B.1.1.7, B.1.351, P.1, B.1.617.2, and C.37, respectively. A total of 328 nucleotide mutation sites were found in 42 genomes, among which A23403G mutation (D614G amino acid change in the spike protein) was the most common substitution. The phylogenetic trees of 42 SARS-CoV-2 sequences and GISAID-available SARS-CoV-2 sequences were constructed and its taxonomic status was supported. These results will provide scientific basis for tracing the source and prevention and control of SARS-CoV-2 imported from abroad in Nanjing, China.

Indexed as

evolutiongenomesphylogenySARS-CoV-2variant

Identifiers

PMID35369437
PMCPMC8969601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.