SynthesisFrontiers in cardiovascular medicine2022
Social Determinants of Disparities in Mortality Outcomes in Congenital Heart Disease: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The Child Opportunity Index and Children's Health: A Meta-Analysis.Pediatrics · 2025Pooled it
- Outcomes of Congenital Heart Disease Deliveries at a Freestanding Children's Hospital.Pediatric cardiology · 2026Article
- Racial and Educational Isolation are Associated with Worse Outcomes in Congenital Heart Disease.Pediatric cardiology · 2026Article
- Article
- Social Determinants of Health in Endoscopic Anterior Skull Base Surgery: A Systematic Review and Meta-Analysis.Laryngoscope investigative otolaryngology · 2025Review
- Social Determinants of Self-Reported Health in Vulnerable Populations During a Polycrisis in Lebanon.JAMA network open · 2025Article
- The Contribution of Social and Structural Determinants of Health Deficits to Mental and Behavioral Health Among a Diverse Group of Young People.International journal of environmental research and public health · 2025Article
- Discrepancies in survival following pediatric heart transplantation and the effect of race and socioeconomic status on outcomes.JTCVS open · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Incidence and predictors of mortality among neonates with congenital heart disease in Ethiopia: a retrospective cohort study.BMC pediatrics · 2024Article
- Addressing Disparities in Pediatric Congenital Heart Disease: A Call for Equitable Health Care.Journal of the American Heart Association · 2024Review
- Racial and Ethnic Disparities in Health Care Usage and Death by Neighborhood Poverty Among Individuals With Congenital Heart Defects, 4 US Surveillance Sites, 2011 to 2013.Journal of the American Heart Association · 2024Article
- Untangling the Complex Associations between Socioeconomic and Demographic Characteristics and Prenatal Detection and Outcomes in Congenital Heart Disease.Journal of cardiovascular development and disease · 2024Review
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Social inequities impact infant mortality due to congenital heart disease.Public health · 2023Article
- Survival From Birth Until Young Adulthood Among Individuals With Congenital Heart Defects: CH STRONG.Circulation · 2023Article
- Does universal insurance influence disparities in high-quality hospital use for inpatient pediatric congenital heart defect care within the first year of diagnosis?BMC health services research · 2023Article
- Neonatal Depression Is Associated With 1-Year Mortality in Critical Congenital Heart Disease.Journal of the American Heart Association · 2023Article
- Racial and Ethnic Disparities in Outcomes Among Newborns with Congenital Diaphragmatic Hernia.JAMA network open · 2023Article
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Social determinants of health (SDoH) affect congenital heart disease (CHD) mortality across all forms and age groups. We sought to evaluate risk of mortality from specific SDoH stratified across CHD to guide interventions to alleviate this risk. Methods: We searched electronic databases between January 1980 and June 2019 and included studies that evaluated occurrence of CHD deaths and SDoH in English articles. Meta-analysis was performed if SDoH data were available in >3 studies. We included race/ethnicity, deprivation, insurance status, maternal age, maternal education, single/multiple pregnancy, hospital volume, and geographic location of patients as SDoH. Data were pooled using random-effects model and outcome was reported as odds ratio (OR) with 95% confidence interval (CI). Results: Of 17,716 citations reviewed, 65 met inclusion criteria. Sixty-three were observational retrospective studies and two prospective. Of 546,981 patients, 34,080 died. Black patients with non-critical CHD in the first year of life (Odds Ratio 1.62 [95% confidence interval 1.47-1.79], I Conclusion: This systematic review and meta-analysis found that Black patients with CHD are particularly vulnerable for mortality. Numerous SDoH that affect mortality were identified for specific time points in CHD course that may guide interventions, future research and policy. Systematic Review Registration: [https://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42019139466&ID=CRD42019139466], identifier [CRD42019139466].
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