Evidence map›Paper›PMID 35369306›Full record

SynthesisFrontiers in cardiovascular medicine2022

WiSE CRT Is Beneficial for Heart Failure Patients as a Rescue Therapy: Evidence From a Meta-Analysis.

Jiehui Cang, Yaowu Liu, Didi Zhu, Shangshang Liu, Junxian Shen, Hongyu Miao, Qianxing Zhou, Long Chen

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiehui CangDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Yaowu LiuDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Didi ZhuDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Shangshang LiuDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Junxian ShenDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Hongyu MiaoDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Qianxing ZhouDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.
Long ChenDepartment of Cardiology, Zhongda Hospital of Southeast University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Leadless endocardial left ventricular (LV) pacing resynchronization therapy is a novel solution for patients with heart failure (HF) in whom conventional cardiac resynchronization therapy (CRT) failed. Methods: PubMed and the Cochrane Library were searched for relevant cohort studies. Clinical outcomes of interest such as ejection fraction (EF), QRS duration (QRSd), and left ventricular end-systolic volume (LVESV) were extracted and analyzed. Results: Five studies involving 175 HF patients for WiSE CRT were included, and patients were followed-up for 6 months. The implanted success rate ranged from 76.5 to 100%. WiSE CRT resulted in significantly narrower QRSd [mean difference (MD): -38.21 ms, 95% confidence interval (CI): -44.36 to -32.07, Conclusion: Evidence from current studies suggests that leadless endocardial LV pacing resynchronization is effective for HF patients who failed conventional CRT or needed a device upgrade, and it may be an interesting rescue therapy.

Indexed as

CRTendocardial pacingheart failureleadless cardiac pacingWiSE system

Identifiers

PMID35369306
PMCPMC8964787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.