Evidence map›Paper›PMID 35369277›Full record

ArticleFuture science OA2022

Demography, patterns of care, and survival outcomes in patients with salivary duct carcinoma: an individual patient data analysis of 857 patients.

Prashanth Giridhar, Bhanu Prasad Venkatesulu, Ryan Yoo, Pragathee V, Goura K Rath, Supriya Mallick, Ashishdutt Upadhyay, Dennis Pai Chan

Abstract read
In one paragraph

Article in Future science OA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Prashanth GiridharDepartment of Radiation Oncology, Tata Medical Centre,Varanasi.
Bhanu Prasad VenkatesuluLoyola University Chicago, Loyola University Medical Center &/or Edward Hines Jr., VA Hospital, Stritch School of Medicine, Department of Radiation Oncology, Cardinal Bernardin Cancer Center, Maywood, IL 60153, USA.ORCID https://orcid.org/0000-0003-2541-2055
Ryan YooLoyola University Chicago, Loyola University Medical Center &/or Edward Hines Jr., VA Hospital, Stritch School of Medicine, Department of Radiation Oncology, Cardinal Bernardin Cancer Center, Maywood, IL 60153, USA.
Pragathee VDepartment of Internal Medicine, Karpagam Faculty of Medical Sciences & Research, Coimbatore, Tamil Nadu, India.
Goura K RathDepartment of Radiation Oncology, All India institute of medical sciences, New Delhi, India.
Supriya MallickDepartment of Radiation Oncology, All India institute of medical sciences, New Delhi, India.
Ashishdutt UpadhyayDepartment of Biostatics, All India Institute of Medical Sciences, New Delhi, India.
Dennis Pai ChanLoyola University Chicago, Loyola University Medical Center &/or Edward Hines Jr., VA Hospital, Stritch School of Medicine, Department of Radiation Oncology, Cardinal Bernardin Cancer Center, Maywood, IL 60153, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Salivary duct carcinoma (SDC) is a rare and aggressive malignancy. The optimal treatment protocols are debated. Methodology: A systematic search and individual patient data analysis of published cases of SDC was performed. SPSS v21 was used for statistical analysis. Results: Data of 857 patients available. Median overall survival (OS) and progression-free survival (PFS) of the entire cohort 42 months and 24 months. Nodal involvement, males, primary size >5 cm, androgen receptor (AR) negativity significantly worse OS. Patients with surgery had a favorable median PFS (p = 0.000) and OS (p = 0.077). Patients with adjuvant radiation had better PFS (30 vs 18 months; p = 0.077). Conclusion: SDC has modest survival. Surgery and adjuvant radiation should be advocated for all patients. AR expression appears prognostic for survival.

Indexed as

adjuvantandrogen deprivation therapyandrogen receptorcarcinomaHer2/neu overexpressionparotidpatterns of careradiotherapysalivary ductsurgery

Identifiers

PMID35369277
PMCPMC8965816

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.