ArticleCurrent opinion in behavioral sciences2021
Applying dense-sampling methods to reveal dynamic endocrine modulation of the nervous system.
Article in Current opinion in behavioral sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 33 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Probing the Role of Feature Dimension Maps in Visual Cognition: Expt 1.1
Probing the Role of Feature Dimension Maps in Visual Cognition: Expt 2.1
Probing the Role of Feature Dimension Maps in Visual Cognition: Expt 2.3
Probing the Role of Feature Dimension Maps in Visual Cognition: Expt 3.1 (Pilot)
Probing the Role of Feature Dimension Maps in Visual Cognition: Expt 1.1 (Behavioral)
Probing the Role of Feature Dimension Maps in Visual Cognition: Expt 2.2
Who cites it
33 citing papers in PubMed.
- A dense-sampling investigation of interoceptive variation across the menstrual cycle: the Cyclic Hormones and Interoception with Repeated Profiling (CHIRP) Study.Brain, behavior, & immunity - health · 2026Article
- Practical considerations for dense longitudinal neuroimaging: Ten simple rules for frequent scanning over short time periods.Developmental cognitive neuroscience · 2026Article
- A cognitive computational framework for ovarian hormone modulation of addiction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Endocrine modulation of cortical and retinal baseline perfusion across the menstrual cycle.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Physiological Mechanisms in Pregnancy and Their Relevance to the Clinical Management of Perinatal Mental Illness.Journal of clinical medicine · 2026Review
- Gendering the Menstrual Cycle in Behavioral Neuroendocrinology.American journal of human biology : the official journal of the Human Biology Council · 2026Review
- The progression of sex differences in brain networks across the lifespan.bioRxiv : the preprint server for biology · 2026Article
- Dense Phenotyping of Human Brain Network Organization Using Precision fMRI.Annual review of psychology · 2026Review
- Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals.Nature neuroscience · 2025Article
- Beyond the optic disc: Investigating gender-based differences in optic neuritis.World journal of clinical cases · 2025Review
- The intrinsic time tracker: temporal context is embedded in entorhinal and hippocampal functional connectivity patterns.Nature communications · 2025Article
- Sex differences in age-associated neurological diseases-A roadmap for reliable and high-yield research.Science advances · 2025Review
- 28 days later: A prospective daily study on psychological well-being across the menstrual cycle and the effects of hormones and oral contraceptives.Psychological medicine · 2025Article
- The neurobiology of plant-based therapeutics in women's reproductive health: mechanisms, efficacy, and clinical translation.Frontiers in nutrition · 2025Review
- Idiosyncrasy and generalizability of contraceptive- and hormone-related functional connectomes across the menstrual cycle.Network neuroscience (Cambridge, Mass.) · 2025Article
- Advances in the fMRI analysis of the default mode network: a review.Brain structure & function · 2024Review
- Longitudinal neuroanatomical increases from early to one-year postpartum.Brain structure & function · 2024Article
- Neuroanatomical changes observed over the course of a human pregnancy.Nature neuroscience · 2024Article
- Beyond Birth Control: The Neuroscience of Hormonal Contraceptives.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Circadian Rhythms Tied to Changes in Brain Morphology in a Densely Sampled Male.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The brain is an endocrine organ whose day-to-day function is tied to the rhythmic production of neuromodulatory hormones. Yet, traditional approaches to studying brain-hormone relationships in humans are often coarse in scope. By contrast, dense-sampling neuroimaging offers the unique ability to probe dynamic interactions between the nervous and endocrine systems. This review summarizes recent evidence of sex hormones' influence on structural and functional properties of the human brain. In particular, findings from the '28andMe' project suggest that estradiol modulates the topology of large-scale functional brain networks and progesterone rapidly shapes medial temporal lobe morphology across the menstrual cycle. This nascent body of work sets the stage for additional studies in larger cohorts. We end by discussing the potential of dense-sampling designs to further elucidate endocrine modulation of the brain, with implications for personalized medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.