Evidence map›Paper›PMID 35368755›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Identification of Potential Poly (ADP-Ribose) Polymerase-1 Inhibitors Derived from

Adel M Abuzenadah, Fatin Al-Sayes, Syed Sahajada Mahafujul Alam, Mehboob Hoque, Sajjad Karim, Ibtessam M R Hussain, Shams Tabrez

RetractedAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Retracted: Identification of Potential Poly (ADP-Ribose) Polymerase-1 Inhibitors Derived fromEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Adel M AbuzenadahDepartment of Medical Laboratory Science, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0003-4969-2071
Fatin Al-SayesCenter of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-7650-3742
Syed Sahajada Mahafujul AlamApplied Bio-Chemistry Lab, Department of Biological Sciences, Aliah University, Kolkata, India.
Mehboob HoqueApplied Bio-Chemistry Lab, Department of Biological Sciences, Aliah University, Kolkata, India.ORCID https://orcid.org/0000-0001-8450-7738
Sajjad KarimCenter of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0003-0907-2097
Ibtessam M R HussainCenter of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0001-9909-9888
Shams TabrezDepartment of Medical Laboratory Science, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0003-4550-415X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly (ADP-ribose) polymerase-1 (PARP-1) has been recognized as a prospective target for the development of novel cancer therapeutics. Several PARP-1 inhibitors are currently being considered for anticancer drug development and clinical investigation. Lately, natural compounds seem to be excellent alternative drug candidates for cancer treatment.

Identifiers

PMID35368755
PMCPMC8967534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.