Evidence map›Paper›PMID 35368704›Full record

ArticleFrontiers in genetics2022

The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes.

Elena Flowers, Alka M Kanaya, Li Zhang, Bradley E Aouizerat

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  12. MicroRNAs Associated With Incident Diabetes in the Diabetes Prevention Program.The Journal of clinical endocrinology and metabolism · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. MicroRNAs and Cancer Racial Disparities.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elena FlowersUniversity of California, San Francisco, Department of Physiological Nursing, San Francisco, CA, United States.
Alka M KanayaUniversity of California, San Francisco, Department of Epidemiology and Biostatistics, San Francisco, CA, United States.
Li ZhangUniversity of California, San Francisco, Department of Epidemiology and Biostatistics, San Francisco, CA, United States.
Bradley E AouizeratNew York University Bluestone Center for Clinical Research, New York, NY, United States.
University of California, San Francisco · USCenter for Clinical Research (United States) · US

Funding

UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
The Impact of Interventions to Treat Incident Diabetes on Circulating microRNAs in the Diabetes Prevention ProgramR01DK124228 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLOWERS, ELENA · 2020 to 2023
$2.3M
Ectopic fat and atherosclerosis in South AsiansK24HL112827 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2013 to 2022
$1.2M
NHLBI NIH HHS K24 HL112827NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK124228
6 · The paper itself

Abstract

Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.

Indexed as

ancestrybiomarkerdiabetesdiabetes prevention programfasting blood glucosemicroRNAprediabetesrace/ethnicity

Identifiers

PMID35368704
PMCPMC8971619
OpenAlexW4220801538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.