Evidence map›Paper›PMID 35368694›Full record

ArticleFrontiers in genetics2022

A Heterozygous LMF1 Gene Mutation (c.1523C>T), Combined With an LPL Gene Mutation (c.590G>A), Aggravates the Clinical Symptoms in Hypertriglyceridemia.

Danxia Guo, Yingchun Zheng, Zhongzhi Gan, Yingying Guo, Sijie Jiang, Fang Yang, Fu Xiong, Hua Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danxia GuoDepartment of Cardiovascular Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yingchun ZhengDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhongzhi GanDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Yingying GuoDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Sijie JiangDepartment of Cardiovascular Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Fang YangDepartment of Fetal Medicine and Prenatal Diagnosis, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Fu XiongDepartment of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Hua ZhengDepartment of Cardiovascular Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertriglyceridemia is an important contributor to atherosclerotic cardiovascular disease (ASCVD) and acute pancreatitis. Familial hypertriglyceridemia is often caused by mutations in genes involved in triglyceride metabolism. Here, we investigated the disease-causing gene mutations in a Chinese family with hypertriglyceridemia and assessed the functional significance

Indexed as

heterozygous mutationhypertriglyceridemialipase maturation factor 1lipoprotein lipasemissense mutation

Identifiers

PMID35368694
PMCPMC8966663

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