Evidence map›Paper›PMID 35368375›Full record

ReviewTherapeutic advances in musculoskeletal disease2022

Digital health interventions for osteoporosis and post-fragility fracture care.

Amit Gupta, Christina Maslen, Madhavi Vindlacheruvu, Richard L Abel, Pinaki Bhattacharya, Paul A Bromiley, Emma M Clark, Juliet E Compston, Nicola Crabtree, Jennifer S Gregory and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in musculoskeletal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. An enhanced Fracture Risk Evaluation Model (FREM) using national health data on morbidity and medications.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
  7. Review
  8. Article
  9. Patient education following vertebral fragility fracture: a scoping review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. A novel fracture liaison service using digital health: impact on mortality in hospitalized elderly osteoporotic fracture patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 1 country.

Amit GuptaMoorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-1046-3784
Christina MaslenHealth Evidence Matters, Bristol, UK.
Madhavi VindlacheruvuAddenbrooke's Hospital, Cambridge, UK.
Richard L AbelImperial College London, London, UK.
Pinaki BhattacharyaThe University of Sheffield, Sheffield, UK.
Paul A BromileyThe University of Manchester, Manchester, UK.
Emma M ClarkUniversity of Bristol, Bristol, UK.
Juliet E CompstonCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Nicola CrabtreeBirmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Jennifer S GregoryUniversity of Aberdeen, Aberdeen, UK.ORCID https://orcid.org/0000-0002-6328-4560
Eleni P KarikiThe University of Manchester, Manchester, UK.
Nicholas C HarveyUniversity of Southampton, Southampton, UK.
Eugene McCloskeyThe University of Sheffield, Sheffield, UK.
Kate A WardUniversity of Southampton, Southampton, UK.
Kenneth E S PooleUniversity of Cambridge School of Clinical Medicine, CB2 0QQ Cambridge, UK.ORCID https://orcid.org/0000-0003-4546-7352
University of Manchester · GBUniversity of Sheffield · GBUniversity of Southampton · GBAddenbrooke's Hospital · GBBirmingham Women’s and Children’s NHS Foundation Trust · GBCambridge University Hospitals NHS Foundation Trust · GBImperial College London · GBMoorfields Eye Hospital NHS Foundation Trust · GBUniversity of Aberdeen · GBUniversity of Bristol · GBUniversity of Cambridge · GB

Funding

Medical Research Council G0400491Medical Research Council MC_PC_21003Medical Research Council MC_PC_21022Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/2
6 · The paper itself

Abstract

The growing burden from osteoporosis and fragility fractures highlights a need to improve osteoporosis management across healthcare systems. Sub-optimal management of osteoporosis is an area suitable for digital health interventions. While fracture liaison services (FLSs) are proven to greatly improve care for people with osteoporosis, such services might benefit from technologies that enhance automation. The term 'Digital Health' covers a variety of different tools including clinical decision support systems, electronic medical record tools, patient decision aids, patient apps, education tools, and novel artificial intelligence (AI) algorithms. Within the scope of this review are AI solutions that use algorithms within health system registries to target interventions. Clinician-targeted, patient-targeted, or system-targeted digital health interventions could be used to improve management and prevent fragility fractures. This review was commissioned by The Royal Osteoporosis Society and Bone Research Academy during the production of the 2020 Research Roadmap (https://theros.org.uk), with the intention of identifying gaps where targeted research funding could lead to improved patient health. We explore potential uses of digital technology in the general management of osteoporosis. Evidence suggests that digital technologies can support multidisciplinary teams to provide the best possible patient care based on current evidence and to support patients in self-management. However, robust randomised controlled studies are still needed to assess the effectiveness and cost-effectiveness of these technologies.

Indexed as

bone densitydigital healthfractureosteoporosis

Identifiers

PMID35368375
PMCPMC8966117
OpenAlexW4225750223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.