ArticleMedicina oral, patologia oral y cirugia bucal2022
Epidemiology and survival outcomes of lip, oral cavity, and oropharyngeal squamous cell carcinoma in a southeast Brazilian population.
Article in Medicina oral, patologia oral y cirugia bucal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07005115 (Analysis of Serum Lipid Profile in Patients With Lip Squamous Cell Carcinoma), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of Serum Lipid Profile in Patients With Lip Squamous Cell Carcinoma
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognostic significance of tertiary lymphoid structures in oral squamous cell carcinomas: a systematic review.Frontiers in oral health · 2024Pooled it
- Effectiveness of Organized Strategies to Enhance Access to Preventive Oral Cancer Screening Among High-Risk Individuals in Brazil: A Randomized Clinical Trial in Primary Care.International journal of cancer · 2026Trial
- Outcomes and Risk Factors in Young Patients with Head-and-Neck Cancer: A Multi-Center Retrospective Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Programmed cell death ligand 1(PD-L1) association in metastatic and non-metastatic oral squamous cell carcinoma: clinicopathologic and immunohistochemical study.Scientific reports · 2026Article
- An Analysis of the Timeline to Diagnosis and Treatment in Oral Cavity and Oropharynx Cancer.Oral diseases · 2026Article
- Sentinel lymph node biopsy in cT1-2N0 lip squamous cell carcinoma: site-specific diagnostic accuracy, anatomic mapping, and survival impact.BMC oral health · 2026Article
- Comparative Analysis of Oral and Oropharyngeal Mucosal Lesions of American Tegumentary Leishmaniasis and Other Infectious Granulomatous Diseases and Squamous Cell Carcinoma.Pathogens (Basel, Switzerland) · 2026Article
- Consequences of interrupted follow-up in head and neck cancer and oral potentially malignant disorders patients due to the COVID-19 pandemic.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Overall survival and prognostic factors of oral cavity and oropharyngeal squamous cell carcinomas in Saudi Arabia: a population-based cohort study (2000-2019).Frontiers in oncology · 2026Article
- Nomograms for predicting prognosis in postoperative lip squamous cell carcinoma patients.Discover oncology · 2025Article
- Assessment of Dental Students' Knowledge and Attitudes About the Epidemiologic and Clinical Characteristics of Oral Cancer: Implications for Other Middle-income Countries.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Burden, trends, projections, and spatial patterns of lip and oral cavity cancer in Iran: a time-series analysis from 1990 to 2040.BMC public health · 2025Article
- Article
- Overall and disease-free survival in patients with HPV-positive and HPV-negative oropharyngeal cancer.Einstein (Sao Paulo, Brazil) · 2025Article
- Development of a Prognostic Nomogram Incorporating the Naples Prognostic Score for Postoperative Oral Squamous Cell Carcinoma Patients.Journal of inflammation research · 2025Article
- Clinicopathologic characteristics of young patients with lip squamous cell carcinoma: a retrospective study.Medicina oral, patologia oral y cirugia bucal · 2024Article
- NTRK Gene Expression Analysis in Oral Squamous Cell Carcinoma Mexican Population.Dentistry journal · 2024Article
- Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.International journal of molecular sciences · 2024Article
- Head and Neck Cancer in Pan-American Notable People: An International Survey.Dentistry journal · 2024Article
- Insights into incipient oral squamous cell carcinoma: a comprehensive south-american study.Medicina oral, patologia oral y cirugia bucal · 2024Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC) represent a major health problem in the global scenario. In South America, the highest incidence rates are seen in Brazil. Therefore, the epidemiological and clinical profile and survival outcomes of lip, oral cavity, and oropharyngeal SCC was studied in São Paulo State, Brazil. MATERIAL AND
methodsThe clinicopathological data of 12,099 patients with lip, oral cavity, and oropharyngeal SCC were obtained from hospital cancer registries of the Fundação Oncocentro de São Paulo, Brazil (2010-2015). Survival rates and other analyses were performed using SPSS software.
resultsA clear male predominance was observed, particularly for patients with oropharyngeal SCC (88.3%). The average age of patients was higher for lip cases (65 ± 13.5 years) compared to other sites. The schooling level was low for most patients, especially in lip cases (87.9%). Most of the patients with oral cavity (71.8%) and oropharyngeal (86.3%) SCC had advanced-stage (III-IV) disease. However, the majority of lip cases (83.3%) were at an early stage (I-II). Surgical excision was the main treatment for lip (72%) and oral cavity SCC (23.5%), and chemoradiotherapy was the main treatment for oropharyngeal SCC (40.2%). The 5-year overall survival (OS) for patients with lip, oral cavity, and oropharyngeal SCC were 66.3, 30.9, and 22.6%, respectively. Multivariate analysis revealed that the determinants of OS were different for lip, oral cavity, and oropharyngeal SCC, except for those at the clinical stage, which was an independent predictor for all sites.
conclusionsOS-independent determinants varied according to the affected site. Oral cavity and oropharyngeal SCC presented worse survival rates than those for lip SCC.
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