Evidence map›Paper›PMID 35367989›Full record

ArticleNeuropsychobiology2022

Validation of the Apraxia Screen TULIA (AST) in Schizophrenia.

Hanta Bachofner, Konstantin A Scherer, Tim Vanbellingen, Stephan Bohlhalter, Katharina Stegmayer, Sebastian Walther

Registry-linked trialAbstract read
In one paragraph

Article in Neuropsychobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07027085 (Investigation of the Effects of Virtual Reality Applications on Sensory Processing, Cognitive Skills, Social Functioning and Disease Symptoms in Individuals Diagnosed With Schizophrenia), which is not on this map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07027085 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Investigation of the Effects of Virtual Reality Applications on Sensory Processing, Cognitive Skills, Social Functioning and Disease Symptoms in Individuals Diagnosed With Schizophrenia

TypeinterventionalSponsorNigde Omer Halisdemir UniversityRan2025 to 2025Enrolled52ConditionsSchizophrenia DisordersArmsvirtual reality
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanta BachofnerTranslational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.
Konstantin A SchererTranslational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.
Tim VanbellingenNeurocenter, Luzerner Kantonsspital, Luzern, Switzerland.
Stephan BohlhalterNeurocenter, Luzerner Kantonsspital, Luzern, Switzerland.
Katharina StegmayerTranslational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.
Sebastian WaltherTranslational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDeficits in social interaction and community functioning, including impaired use, performance, and perception of hand gestures, are key features in schizophrenia. A well-established tool to assess gesture deficits is the test of upper limb apraxia (TULIA). However, given its time-consuming application based on video analyses, research has proposed the bedside apraxia screen of TULIA (AST). This study aims to test the validity and reliability of the AST to detect gesture abnormalities at bedside in a sample of 27 patients diagnosed with schizophrenia, schizotypal disorder, acute and transient psychotic disorders, or schizoaffective disorder.

methodsPatients completed the 48-item TULIA and the 12-item AST. Two different raters assessed the AST: one at bedside (online) and the other based on the video recordings.

resultsThe total AST scores demonstrated a high parallel reliability, moderate inter-rater reliability on a single-item level, and good construct validities.

conclusionsThe psychometric properties of the AST suggest it can well be used for the clinical assessment of gesture deficits in schizophrenia. However, when detailed information is required, the AST rated from video or conducting the full TULIA is recommended. The findings call for refining the selection of the TULIA items for a psychosis-AST bedside test to increase specificity.

Indexed as

ApraxiasPsychotic DisordersSchizophreniaGesturesHumansReproducibility of ResultsASTHand gesturesNonverbal communicationSchizophrenia spectrum disordersTULIA

Identifiers

PMID35367989
PMCPMC9533426

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.