Evidence map›Paper›PMID 35367901›Full record

ArticleUltramicroscopy2022

On the reduction in the effects of radiation damage to two-dimensional crystals of organic and biological molecules at liquid-helium temperature.

Katerina Naydenova, Akiko Kamegawa, Mathew J Peet, Richard Henderson, Yoshinori Fujiyoshi, Christopher J Russo

Open access · hybridAbstract read
In one paragraph

Article in Ultramicroscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Ultracold cryogenic TEM with liquid helium and high stability.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Extending the reach of single-particle cryoEM.Current opinion in structural biology · 2025
    Review
  5. Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Charting the molecular landscape of the cell.Structure (London, England : 1993) · 2023
    Review
  9. CryomicroscopyFaraday discussions · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Katerina NaydenovaMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Akiko KamegawaCellular and Structural Physiology Laboratory (CeSPL), Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan.
Mathew J PeetMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Richard HendersonMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Yoshinori FujiyoshiCellular and Structural Physiology Laboratory (CeSPL), Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan.
Christopher J RussoMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address: crusso@mrc-lmb.cam.ac.uk.
MRC Laboratory of Molecular Biology · GBTokyo Medical and Dental University · JP

Funding

Medical Research Council MC_U105184322Medical Research Council MC_UP_1201/17Medical Research Council MC_UP_120117Wellcome TrustWellcome Trust 220526/B/20/Z
6 · The paper itself

Abstract

We have studied the fading of electron diffraction spots from two-dimensional (2D) crystals of paraffin (C

Indexed as

HeliumNitrogenCryoelectron MicroscopyMacromolecular SubstancesTemperatureHeliumMacromolecular SubstancesNitrogen2D crystallographycryoEMCryomicroscopyLiquid heliumRadiation damage

Identifiers

PMID35367901
PMCPMC9355890
OpenAlexW4220926828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.