SynthesisBMC complementary medicine and therapies2022
Complementary and alternative medicine modalities used to treat adverse effects of anti-cancer treatment among children and young adults: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Safety of Complementary and Alternative Medicine (CAM) treatment among children and young adults who suffer from adverse effects of conventional cancer treatment: A systematic review.Integrative cancer therapiesPooled it
- Pediatric Hematology-Oncology Provider Attitudes and Beliefs About the Use of Acupuncture for Their Patients.Children (Basel, Switzerland) · 2025Article
- Acupuncture and moxibustion in integrative oncology and new progress in China.Integrative medicine research · 2025Review
- Study of Complementary and Integrative Interventions in Pediatric Patients With Serious Illness.Journal of pain and symptom management · 2025Article
- Effect of group music therapy on state-anxiety and well-being levels of oncology patients undergoing chemotherapy: a multi-center randomized clinical trial.Frontiers in psychiatry · 2025Article
- Trial Sequential Analysis and Meta-Analysis of Olanzapine in Pediatric Patients for Chemotherapy-Induced Nausea and Vomiting (CINV).Hospital pharmacy · 2024Review
- Complementary and alternative medicine use among cancer patients in Iran: A systematic review.Preventive medicine reports · 2024Article
- Use of complementary and alternative medicine in children affected by oncologic, neurologic and liver diseases: a narrative review.Italian journal of pediatrics · 2023Review
- Supportive care for cancer-related symptoms in pediatric oncology: a qualitative study among healthcare providers.BMC complementary medicine and therapies · 2023Article
- A Historical Misconception in Clinical Trials of Drugs for Cancer-Age Grouping.Journal of personalized medicine · 2022Article
- Cardiovascular Effects ofEvidence-based complementary and alternative medicine : eCAM · 2022Review
- Safety of Acupuncture Using Semi-Permanent Needles in a Pediatric Cancer Unit: A Retrospective Study.Integrative cancer therapiesObservational
- A Qualitative Study Among Healthcare Providers on Risks Associated With the Use of Supportive Care for Cancer Treatment-Related Symptoms in Children and Adolescents.Integrative cancer therapiesArticle
- Non-pharmacological interventions for side effects of antineoplastic chemotherapy prioritized by patients: systematic review.Revista CuidarteArticle
- The Use of Complementary and Integrative Medicine in Combination With Pharmacological Antiemetics to Address Chemotherapy-Induced Nausea and Vomiting in Pediatric Oncology: A Scoping Review.Journal of pediatric hematology/oncology nursingArticle
- Development of the Intervention Protocol for the Study of Creative Arts Among Children With Cancer.Journal of pediatric hematology/oncology nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDealing with the symptom burden of cancer diagnosis and treatment has led parents to seek different self-management strategies including Alternative and Complementary Medicine (CAM). The aim of this study was to perform a systematic review and meta-analysis about the use and effect of CAM modalities to treat adverse effects of conventional cancer treatment among children and young adults.
methodsSix scientific research databases were used to identify randomized controlled trials (RCTs) from 1990 to September 2020. Included studies investigated the use of CAM to treat cancer treatment related adverse effects in children and young adults compared to controls.
resultsTwenty RCTs comprising 1,069 participants were included in this review. The included studies investigated acupuncture, mind-body therapies, supplements, and vitamins for chemotherapy-induced nausea and vomiting (CINV), oral mucositis, and anxiety among children and young adults who underwent conventional cancer treatment. Seven studies (315 participants) were included in the meta-analysis. The overall effect of CAM (including acupuncture and hypnosis only) on chemotherapy-induced nausea and/or vomiting and controls was statistically significant with a standard mean difference of -0.54, 95% CI [-0.77, -0.31] I
conclusionCurrent evidence from this meta-analysis of randomized controlled trials shows that CAM, including acupuncture and hypnosis only, is effective in reducing chemotherapy-induced nausea and vomiting in children and young adults. More rigorous trials and long-term effects should be investigated if acupuncture and hypnosis are to be recommended for clinical use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.