Evidence map›Paper›PMID 35366857›Full record

ArticleBMC palliative care2022

Intensive end-of-life care in acute leukemia from a French national hospital database study (2017-2018).

Sébastien Salas, Vanessa Pauly, Margaux Damge, Veronica Orleans, Guillaume Fond, Régis Costello, Laurent Boyer, Karine Baumstarck

Abstract read
In one paragraph

Article in BMC palliative care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sébastien SalasDepartment of Palliative Care, Oncology, APHM, Marseille, France.
Vanessa PaulyDepartment of Medical Information, APHM, Marseille, France.
Margaux DamgeDepartment of Palliative Care, Oncology, APHM, Marseille, France.
Veronica OrleansDepartment of Medical Information, APHM, Marseille, France.
Guillaume FondDepartment of Medical Information, APHM, Marseille, France.
Régis CostelloHematology and Cellular Therapy Department, APHM, Marseille, France.
Laurent BoyerDepartment of Medical Information, APHM, Marseille, France.
Karine BaumstarckCEReSS - Health Service Research and Quality of Life Center, Aix-Marseille University, EA 3279, 27 bd Jean Moulin, cedex 05, F-13385, Marseille, France. karine.baumstarck@univ-amu.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA better understanding of how the care of acute leukemia patients is managed in the last days of life would help clinicians and health policy makers improve the quality of end-of-life care. This study aimed: (i) to describe the intensity of end-of-life care among patients with acute leukemia who died in the hospital (2017-2018) and (ii) to identify the factors associated with the intensity of end-of-life care.

methodsThis was a retrospective cohort study of decedents based on data from the French national hospital database. The population included patients with acute leukemia who died during a hospital stay between 2017 and 2018, in a palliative care situation (code palliative care Z515 and-or being in a inpatient palliative care support bed during the 3 months preceding death). Intensity end-of-life care was assessed using two endpoints: High intensive end-of-life (HI-EOL: intensive care unit admission, emergency department admission, acute care hospitalization, intravenous chemotherapy) care and most invasive end-of-life (MI-EOL: orotracheal intubation, mechanical ventilation, artificial feeding, cardiopulmonary resuscitation, gastrostomy, or hemodialysis) care.

resultsA total of 3658 patients were included. In the last 30 days of life, 63 and 13% of the patients received HI-EOL care and MI-EOL care, respectively. Being younger, having comorbidities, being care managed in a specialized hospital, and a lower time in a palliative care structure were the main factors associated with HI-EOL.

conclusionsA large majority of French young adults and adults with acute leukemia who died at the hospital experienced high intensity end-of-life care. Identification of factors associated with high-intensity end-of-life care, such as the access to palliative care and specialized cancer center care management, may help to improve end-of-life care quality.

Indexed as

Hospice CareLeukemiaTerminal CareHospitalsHumansRetrospective StudiesYoung AdultAcute leukemiaEnd-of-life careHealth services researchPalliative careRegistry database

Identifiers

PMID35366857
PMCPMC8976296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.