Evidence map›Paper›PMID 35366827›Full record

ReviewBMC ophthalmology2022

Kimura's disease successively affecting multiple body parts: a case-based literature review.

Baodi Yang, Hailan Liao, Minghua Wang, Qiaoyan Long, Huanhuan Zhong, Lin Luo, Zhongmin Liu, Xiaohui Cheng

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Kimura disease presenting as epiglottic masses: A case report.The Journal of international medical research · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Clinical heterogeneity and prognostic markers in head and neck Kimura disease: A retrospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Comparative Imaging Analysis of Kimura's Disease UsingJournal of inflammation research · 2025
    Article
  12. Article
  13. Characteristics ofBMC medical imaging · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Baodi YangDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China. yangbaodi_8651@163.com.ORCID http://orcid.org/0000-0002-0315-2179
Hailan LiaoDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Minghua WangDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Qiaoyan LongDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Huanhuan ZhongDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Lin LuoDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Zhongmin LiuDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Xiaohui ChengDepartment of Ophthalmology, Longgang District People's Hospital of Shenzhen, No.53 Aixin Road, Longgang District, Shenzhen, 518172, China.
Longgang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKimura's disease is a rare, benign, chronic inflammatory disease that presents as painless, solid masses mainly affecting the deep subcutaneous areas of the head and neck, especially the salivary glands, parotid glands and nearby lymph nodes. It is characterized by elevated peripheral blood eosinophil and Immunoglobulin E (IgE) levels. CASE PRESENTATION: A 31-year-old Asian male presented with an orbital space-occupying lesion lasting for 1.5 years. Ten years prior, surgical excision of bilateral fossa cubitalis and groin masses was performed, and the pathological examination showed "lymphoproliferative disease". One year later, masses reappeared near the surgical sites; they grew slowly and shrank after glucocorticoid treatment. At this point, admission examinations showed in the peripheral blood an eosinophil proportion of 13.4%, a total IgE level of 26,900.00 IU/mL, prurigo present on the whole body, and multiple palpable masses near the bilateral fossa cubitalis and groin. The left eyeball was exophthalmic. The left elbow mass was excised, and the pathological examination confirmed Kimura's disease. Oral glucocorticoid therapy is taken and tapering regularly. The eosinophil count returned to normal, the IgE level gradually decreased, the orbital space-occupying lesion and elbow and groin masses shrank significantly, and the whole-body skin prurigo disappeared. Currently, the patient has been in a stable condition for eighteen months.

conclusionOur case provides a novel insight that Kimura's disease should be involved in the differential diagnosis of inflammatory lesion mass of orbit and also supports systemic regular glucocorticoid as a valuable therapy of such condition, but close follow-up and long-term observation are crucial.

Indexed as

Angiolymphoid Hyperplasia with EosinophiliaKimura DiseaseAdultDiagnosis, DifferentialHuman BodyHumansMaleNeckEosinophilsFossa CubitalisGroinImmunoglobulin EKimura’s diseaseOrbit

Identifiers

PMID35366827
PMCPMC8977031
OpenAlexW4223905793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.