ArticleBMC genomics2022
Genome-wide survey of the GATA gene family in camptothecin-producing plant Ophiorrhiza pumila.
Article in BMC genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 22 citations in OpenAlex.
- Genome-wide in-silico characterization and expression pattern analysis of GATA transcription factor family in carrot (Daucus carota subsp. sativus).Functional & integrative genomics · 2026Article
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- Pan-Genome-Wide Investigation and Expression Analysis ofPlants (Basel, Switzerland) · 2025Article
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- Comparative analysis of the GATA transcription factors in sevenFrontiers in plant science · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2024Article
- Genome-Wide Identification and Characterization of the Sweet Orange (International journal of molecular sciences · 2024Article
- Genome-wide identification of GATA transcription factor family and the effect of different light quality on the accumulation of terpenoid indole alkaloids in Uncaria rhynchophylla.Plant molecular biology · 2024Article
- Genome-wide identification of theFrontiers in plant science · 2024Article
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- Heat responsive geneFrontiers in plant science · 2023Article
- Genome-Wide Identification, Evolution, and Expression Pattern Analysis of theInternational journal of molecular sciences · 2022Article
- Genome-wide comparative analyses of GATA transcription factors among seven Populus genomes.Scientific reports · 2021Article
- Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOphiorrhiza pumila (Rubiaceae) is capable of producing camptothecin (CPT), one monoterpene indole alkaloid extensively employed in the treatment of multiple cancers. Transcription factors (TFs) GATA are a group of transcription regulators involved in plant development and metabolism, and show the feature of binding to the GATA motif within the promoters of target genes. However, GATA TFs have not been characterized in O. pumila.
resultIn this study, a total of 18 GATA genes classified into four subfamilies were identified, which randomly distributed on 11 chromosomes of O. pumila. Synteny analysis of GATA genes between O. pumila and other plant species such as Arabidopsis thaliana, Oryza sativa, Glycine max, Solanum lycopersicum, Vitis vinifera, and Catharanthus roseus genomes were analyzed. Tissue expression pattern revealed that OpGATA1 and OpGATA18 were found to be correlated with ASA, MK, CPR and GPPS, which were highly expressed in leaves. OpGATA7, showed high expression in roots as most of the CPT biosynthetic pathway genes did, suggesting that these OpGATAs may be potential candidates regulating CPT biosynthesis in O. pumila.
conclusionsIn this study, we systematically analyzed the OpGATA TFs, and provided insights into the involvement of OpGATA TFs from O. pumila in CPT biosynthesis.
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