Evidence map›Paper›PMID 35366692›Full record

ArticleArchives of women's mental health2022

The sexual and reproductive health of women with mental illness: a primary care registry study.

Holly Hope, Matthias Pierce, Edward D Johnstone, Jenny Myers, Kathryn M Abel

Open access · hybridAbstract read
In one paragraph

Article in Archives of women's mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Preconception indicators and associations with health outcomes reported in UK routine primary care data: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Pooled it
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  6. Association between sleep quality and life satisfaction and self-efficacy among women with gynecological cancer in West China: A cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  17. Contraceptive use in women with mental illness in Soweto, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Holly HopeCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology Medicine and Health, University of Manchester, Room 3.320 Jean Mac Farlane Building, Oxford Road, Manchester, M13 9PL, UK. holly.hope@manchester.ac.uk.ORCID http://orcid.org/0000-0002-4834-6719
Matthias PierceCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology Medicine and Health, University of Manchester, Room 3.320 Jean Mac Farlane Building, Oxford Road, Manchester, M13 9PL, UK.ORCID http://orcid.org/0000-0003-2182-0369
Edward D JohnstoneMaternal & Fetal Health Research Centre, Division of Developmental Biology & Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0001-9732-8544
Jenny MyersMaternal & Fetal Health Research Centre, Division of Developmental Biology & Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0003-0913-2096
Kathryn M AbelCentre for Women's Mental Health, Division of Psychology and Mental Health, Faculty of Biology Medicine and Health, University of Manchester, Room 3.320 Jean Mac Farlane Building, Oxford Road, Manchester, M13 9PL, UK.ORCID http://orcid.org/0000-0003-3538-8896
Manchester Academic Health Science Centre · GBGreater Manchester Mental Health NHS Foundation Trust · GBUniversity of Manchester · GB

Funding

Department of Health 111905
6 · The paper itself

Abstract

The purpose of this study is to characterise the sexual and reproductive health risks associated with mental illness among women. This was a retrospective cohort study of 2,680,149 women aged 14 to 45 years in the Clinical Practice Research Datalink, a UK primary care register, linked to 1,702,211 pregnancies that ended between the 1st January 1990 and 31st December 2017. Mental illness was identified in primary care and categorised into the following: common mental illness (depression/anxiety); addiction (alcohol/drug misuse); serious mental illness (affective/non-affective psychosis); other mental illness (eating/personality disorders). Logistic regression estimated the association between mental illness and subsequent risk of recurrent miscarriage and termination. Cox proportional hazards estimated the association between mental illness and time to gynaecological diseases, sexually transmitted infections, reproductive cancers, cervical screen, contraception and emergency contraception. Models were adjusted for calendar year, year of birth, smoking status and ethnicity, region and index of socioeconomic status. Compared to women without mental illness, exposed women were more likely to experience recurrent miscarriage (adjOR = 1.50, 95%CI 1.41 to 1.60), termination (adjOR = 1.48, 95%CI 1.45 to 1.50), gynaecological diseases (adjHR = 1.39, 95%CI 1.37 to 1.40), sexually transmitted infections (adjHR = 1.47, 95%CI 1.43 to 1.51), reproductive cancers (adjHR = 1.10, 95%CI 1.02 to 1.19), contraception (adjHR = 1.28 95%CI 1.26 to 1.29) and emergency contraception (adjHR = 2.30, 95%CI 2.26 to 2.34), and less likely to attend for cervical screening (adjHR = 0.91, 95%CI 0.90 to 0.92). Currently, the sexual and reproductive health needs of women with mental illness are unmet representing significant health inequalities. Clinicians must create opportunities to engage with women in primary care and mental health services to address this gap.

Indexed as

Mental DisordersReproductive HealthSexual HealthAbortion, HabitualAdolescentAdultEarly Detection of CancerFemaleHumansMiddle AgedPregnancyPrimary Health CareRegistriesRetrospective StudiesSexually Transmitted DiseasesUterine Cervical NeoplasmsCervical screeningContraceptionFertilityMental illnessReproductive healthSexual health

Identifiers

PMID35366692
PMCPMC9072520
OpenAlexW4225625507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.