Evidence map›Paper›PMID 35366562›Full record

ArticleEcotoxicology and environmental safety2022

Characterization of vitellogenin concentration in male fathead minnow mucus compared to plasma, and liver mRNA.

Mary Jean See, David C Bencic, Robert W Flick, Jim Lazorchak, Adam D Biales

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecotoxicology and environmental safety, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mary Jean SeeUS EPA Office of Research and Development, Center for Computational Toxicology and Exposure, Cincinnati, OH, USA.
David C BencicUS EPA Office of Research and Development, Center for Computational Toxicology and Exposure, Cincinnati, OH, USA.
Robert W FlickUS EPA Office of Research and Development, Center for Computational Toxicology and Exposure, Cincinnati, OH, USA.
Jim LazorchakUS EPA Office of Research and Development, Center for Environmental Measurement and Modeling, Cincinnati, OH, USA.
Adam D BialesUS EPA Office of Research and Development, Center for Computational Toxicology and Exposure, Cincinnati, OH, USA. Electronic address: biales.adam@epa.gov.
Environmental Protection Agency · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

The objective of this study was to characterize vitellogenin (VTG) protein in male fathead minnow (Pimephales promelas) mucus compared with more conventional measures in plasma and mRNA isolated from liver. To assess the intensity and duration of changes in mucus VTG concentrations, male fathead minnows were exposed to 17α-ethinylestradiol (EE2) for 7 days with a subsequent depuration period of 14 days. The experiment was conducted in a flow-through system to maintain a consistent concentration of EE2 at a nominal EC

Indexed as

CyprinidaeVitellogeninsAnimalsLiverMaleMucusRNA, MessengerRNA, MessengerVitellogeninsBiomarkersBiomonitoringELISAEstrogenic compoundsGene expressionRT-qPCR

Identifiers

PMID35366562
PMCPMC9109421
OpenAlexW4220676065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.