Evidence map›Paper›PMID 35366502›Full record

ReviewCurrent opinion in chemical biology2022

Extending optical chemical tools and technologies to mice by shifting to the shortwave infrared region.

Kelly C Y Wong, Ellen M Sletten

Abstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. High-Resolution Multicolor Shortwave Infrared DynamicJournal of the American Chemical Society · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Rejuvenating old fluorophores with new chemistry.Current opinion in chemical biology · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kelly C Y WongDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California, 90095, United States.
Ellen M SlettenDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California, 90095, United States. Electronic address: sletten@chem.ucla.edu.

Funding

Biocompatible fluorophores for shortwave infrared imagingR01EB027172 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Ellen May Sletten · 2019 to 2026
$2.9M
Robust microdroplet-based mechanical probes for wide-ranging mechanobiology applicationsR01GM135380 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CAMPAS, OTGER, SLETTEN, ELLEN MAY · 2019 to 2022
$1.8M
NIBIB NIH HHS R01 EB027172NIGMS NIH HHS R01 GM135380
6 · The paper itself

Abstract

Fluorescence imaging is an indispensable method for studying biological processes non-invasively in cells and transparent organisms. Extension into the shortwave infrared (SWIR, 1000-2000 nm) region of the electromagnetic spectrum has allowed for imaging in mammals with unprecedented depth and resolution for optical imaging. In this review, we summarize recent advances in imaging technologies, dye scaffold modifications, and incorporation of these dyes into probes for SWIR imaging in mice. Finally, we offer an outlook on the future of SWIR detection in the field of chemical biology.

Indexed as

Fluorescent DyesOptical ImagingAnimalsMammalsMiceFluorescent DyesConfocal microscopyFluorogenic probeFluorophoreLight-sheet microscopyMolecular imagingMulticolor imagingMultiplexed imagingRatiometric probeShortwave infraredSmall molecule dyeTargeted imaging

Identifiers

PMID35366502
PMCPMC9583727

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.