Evidence map›Paper›PMID 35366262›Full record

ArticlePathophysiology : the official journal of the International Society for Pathophysiology2021

Implication of RAS in Postnatal Cardiac Remodeling, Fibrosis and Dysfunction Induced by Fetal Undernutrition.

Pilar Rodríguez-Rodríguez, Maria Sofía Vieira-Rocha, Begoña Quintana-Villamandos, Ignacio Monedero-Cobeta, Parichat Prachaney, Angel Luis López de Pablo, Maria Del Carmen González, Manuela Morato, Carmen Diniz, Silvia M Arribas

Open access · goldAbstract read
In one paragraph

Article in Pathophysiology : the official journal of the International Society for Pathophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Pilar Rodríguez-RodríguezFOSCH Group, Department of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
Maria Sofía Vieira-RochaLAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0003-2750-4746
Begoña Quintana-VillamandosDepartment of Anesthesiology, Hospital Universitario Gregorio Marañón, 28009 Madrid, Spain.
Ignacio Monedero-CobetaFOSCH Group, Department of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.ORCID 0000-0001-6370-0467
Parichat PrachaneyCardiovascular Research Group, Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Angel Luis López de PabloFOSCH Group, Department of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
Maria Del Carmen GonzálezFOSCH Group, Department of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.ORCID 0000-0002-5522-0786
Manuela MoratoLAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-9509-0613
Carmen DinizLAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0003-4668-9360
Silvia M ArribasFOSCH Group, Department of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
Universidad Autónoma de Madrid · ESUniversidade do Porto · PTKhon Kaen University · THUniversidad Complutense de Madrid · ES

Funding

1) Ministerio de Ciencia, Innovación y Universidades from Spain and 2) FCT/MCTES, Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior RTI2018-097504-B-I00 and UIDB/50006/2020
6 · The paper itself

Abstract

Fetal undernutrition is a risk factor for cardiovascular diseases. Male offspring from rats exposed to undernutrition during gestation (MUN) exhibit oxidative stress during perinatal life and develop cardiac dysfunction in ageing. Angiotensin-II is implicated in oxidative stress-mediated cardiovascular fibrosis and remodeling, and lactation is a key developmental window. We aimed to assess if alterations in RAS during lactation participate in cardiac dysfunction associated with fetal undernutrition. Control dams received food

Indexed as

angiotensin IIcardiovascular remodelingfetal programmingfibrosislactationleft ventricular hypertrophyRAS receptors

Identifiers

PMID35366262
PMCPMC8830479
OpenAlexW3169995050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.