ArticleEuropean journal of applied physiology2022
Corticomuscular coherence is reduced in relation to dorsiflexion fatigability to the same extent in adults with cerebral palsy as in neurologically intact adults.
Article in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Dynamics of brain-muscle interaction with neuromuscular fatigability: systematic review.Frontiers in physiology · 2026Review
- Neural control meets biomechanics in the motor assessment of neurological disorders: a narrative review.Frontiers in neural circuits · 2025Review
- The neuromechanical of Beta-band corticomuscular coupling within the human motor system.Frontiers in neuroscience · 2024Review
- Effects of Muscle Fatigue and Recovery on the Neuromuscular Network after an Intermittent Handgrip Fatigue Task: Spectral Analysis of Electroencephalography and Electromyography Signals.Sensors (Basel, Switzerland) · 2023Article
- Effects of high-definition transcranial direct current stimulation on the cortical-muscular functional coupling and muscular activities of ankle dorsi-plantarflexion under running-induced fatigue.Frontiers in physiology · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
purposeFatigue is frequent in adults with cerebral palsy (CP) and it is unclear whether this is due to altered corticospinal drive. We aimed to compare changes in corticospinal drive following sustained muscle contractions in adults with CP and neurologically intact (NI) adults.
methodsFourteen adults with CP [age 37.6 (10.1), seven females, GMFCS levels I-II] and ten NI adults [age 35.4 (10.3), 6 females] performed 1-min static dorsiflexion at 30% of maximal voluntary contraction (MVC) before and after a submaximal contraction at 60% MVC. Electroencephalography (EEG) and electromyography (EMG) from the anterior tibial muscle were analyzed to quantify the coupling, expressed by corticomuscular coherence (CMC).
resultsAdults with CP had lower MVCs but similar time to exhaustion during the relative load of the fatigability trial. Both groups exhibited fatigability-related changes in EMG median frequency and EMG amplitude. The CP group showed lower beta band (16-35 Hz) CMC before fatigability, but both groups decreased beta band CMC following fatigability. There was a linear correlation between decrease of beta band CMC and fatigability-related increase in EMG.
conclusionFatigability following static contraction until failure was related to decreased beta band CMC in both NI adults and adults with CP. Our findings indicate that compensatory mechanisms to fatigability are present in both groups, and that fatigability affects the corticospinal drive in the same way. We suggest that the perceived physical fatigue in CP is related to the high relative load of activities of daily living rather than any particular physiological mechanism.
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