ArticleActa paediatrica (Oslo, Norway : 1992)2022
Weight gain in infancy and markers of cardiometabolic health in young adulthood.
Article in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Breastfeeding type is associated with urinary metabolic changes in early life: influence of sex and early weight gain in healthy term infants.Molecular and cellular pediatrics · 2026Article
- Maternal and child predictors of vascular health in infancy and early childhood.Pediatric research · 2026Article
- Association between placental epigenetic age acceleration and early postnatal growth patterns.Scientific reports · 2025Article
- Weight gain in infancy and markers of cardiometabolic health in young adulthood.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
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Abstract
aimWe studied whether repeatedly measured weight gain from birth up to age 2 years associated with cardiometabolic health in young adulthood.
methodsUsing the data collected in the longitudinal Special Turku Coronary Risk Factor Intervention Project, we investigated in 454 healthy subjects how early weight gain in six age intervals (birth to 7 months, 7-13 months, 13-18 months, 18-24 months, and birth to 13 and 24 months) associated with measures of cardiometabolic health at age 20 years. Linear regression analyses were controlled for (1) child's sex, intervention/control group, gestational age, baseline weight and change in length for each interval, and (2) parents' education, mother's weight before pregnancy, height and weight gain during pregnancy, and father's body mass index at the 7-month visit.
resultsWeight gain after the first year of life associated directly, when adjusted for traits of the child and parents, with systolic blood pressure, waist circumference and body mass index at age 20 years. In the fully adjusted analyses, weight gain from birth to 1 year and to 2 years of age associated inversely with insulin and insulin resistance. We found no association between early growth and diastolic blood pressure or serum lipids.
conclusionEarly weight gain during first 2 years of life may predict later markers of cardiometabolic health.
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