Evidence map›Paper›PMID 35365898›Full record

ArticleJournal of neuroendocrinology2022

Gene expression changes in the brain of a Cushing's syndrome mouse model.

Jorge Miguel Amaya, Eva M G Viho, Hetty C M Sips, Reshma A Lalai, Isabelle Sahut-Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Alberto M Pereira, Antoine Martinez, Onno C Meijer

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neuroendocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Jorge Miguel AmayaDepartment of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-5382-5183
Eva M G VihoDepartment of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-1505-6598
Hetty C M SipsDepartment of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.
Reshma A LalaiDepartment of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.
Isabelle Sahut-BarnolaGénétique Reproduction et Développement, Université Clermont-Auvergne, CNRS, INSERM, Clermont-Ferrand, France.
Typhanie DumontetGénétique Reproduction et Développement, Université Clermont-Auvergne, CNRS, INSERM, Clermont-Ferrand, France.ORCID 0000-0002-1328-9515
Nathanaëlle MontanierGénétique Reproduction et Développement, Université Clermont-Auvergne, CNRS, INSERM, Clermont-Ferrand, France.ORCID 0000-0003-2748-5610
Alberto M PereiraDepartment of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-1194-9866
Antoine MartinezGénétique Reproduction et Développement, Université Clermont-Auvergne, CNRS, INSERM, Clermont-Ferrand, France.ORCID 0000-0001-9304-5061
Onno C MeijerDepartment of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-8394-6859
Leiden University Medical Center · NLCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excess glucocorticoid exposure affects emotional and cognitive brain functions. The extreme form, Cushing's syndrome, is adequately modelled in the AdKO

Indexed as

Cushing SyndromeAnimalsBrainGene ExpressionGlucocorticoidsHumansMiceReceptors, GlucocorticoidGlucocorticoidsReceptors, GlucocorticoidbrainCushing's syndromegliaglucocorticoidneuron

Identifiers

PMID35365898
PMCPMC9287025
OpenAlexW4220674346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.