Evidence map›Paper›PMID 35365884›Full record

ArticleMedical physics2022

Conformance of a 3T radiotherapy MRI scanner to the QIBA Diffusion Profile.

Madeline E Carr, Kathryn E Keenan, Robba Rai, Michael A Boss, Peter Metcalfe, Amy Walker, Lois Holloway

Open access · hybridAbstract read
In one paragraph

Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Madeline E CarrCentre for Medical and Radiation Physics, University of Wollongong, Wollongong, Australia.
Kathryn E KeenanPhysical Measurement Laboratory, National Institute of Standards and Technology, Boulder, USA.
Robba RaiMedical Physics, Ingham Institute for Applied Medical Research, Liverpool, Australia.
Michael A BossImaging Core Laboratory, American College of Radiology, Philadelphia, USA.
Peter MetcalfeCentre for Medical and Radiation Physics, University of Wollongong, Wollongong, Australia.
Amy WalkerCentre for Medical and Radiation Physics, University of Wollongong, Wollongong, Australia.
Lois HollowayCentre for Medical and Radiation Physics, University of Wollongong, Wollongong, Australia.
Ingham Institute · AUUniversity of Wollongong · AUAmerican College of Radiology · USCooperative Trials Group for Neuro-Oncology · AUNational Institute of Standards and Technology · US

Funding

South Western Sydney Local Health DistrictSWSLHD Early Researchers Program Grants
6 · The paper itself

Abstract

purposeTo assess the technical performance of the apparent diffusion coefficient (ADC) on a dedicated 3T radiotherapy scanner, using a standardized phantom and sequences. Investigations into factors that could impact the technical performance of ADC in the clinic were also completed, including changing the slice-encoded imaging direction and the reference sample ADC value.

methodsADC acquisitions were performed monthly on an isotropic diffusion phantom over 1 year. Measurements of ADC %bias, coefficients of variation for short-/long-term repeatability and precision (CV

resultsThe average of all measurements over the year was within Profile recommended ranges. This included when testing was performed in different imaging directions, and on samples that had different ADC reference values (0.4-1.1 μm

conclusionsThe technical performance of ADC on a radiotherapy dedicated MRI scanner over the course of 12 months was considered conformant to the QIBA Profile. Quantifying these metrics and factors that may affect the performance is essential in progressing the use of ADC clinically: ensuring that the observed change of ADC in a tissue is due to a physiological response and not measurement variability.

Indexed as

Diffusion Magnetic Resonance ImagingMagnetic Resonance ImagingBiomarkersPhantoms, ImagingReproducibility of ResultsBiomarkersapparent diffusion coefficientdiffusion-weighted imagingquantitative imaging biomarker alliancequantitative magnetic resonance imagingreproducibility

Identifiers

PMID35365884
PMCPMC9543906
OpenAlexW4223433095

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.