Evidence map›Paper›PMID 35365724›Full record

ArticleScientific reports2022

Analysis of individual-level data from 2018-2020 Ebola outbreak in Democratic Republic of the Congo.

Harley Vossler, Pierre Akilimali, Yuhan Pan, Wasiur R KhudaBukhsh, Eben Kenah, Grzegorz A Rempała

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Towards Inferring Network Properties from Epidemic Data.Bulletin of mathematical biology · 2023
    Article
  9. Projecting COVID-19 cases and hospital burden in Ohio.Journal of theoretical biology · 2023
    Article
  10. Article
  11. COVID-19 dynamics in an Ohio prison.Frontiers in public health · 2023
    Article
  12. Dynamic survival analysis for non-Markovian epidemic models.Journal of the Royal Society, Interface · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Harley VosslerCollege of Public Health, The Ohio State University, Columbus, OH, USA.
Pierre AkilimaliCollege of Public Health, University of Kinshasa, Kinshasa, Congo.
Yuhan PanCollege of Public Health, The Ohio State University, Columbus, OH, USA.
Wasiur R KhudaBukhshSchool of Mathematical Sciences, University of Nottingham, Nottingham, UK.
Eben KenahCollege of Public Health, The Ohio State University, Columbus, OH, USA.
Grzegorz A RempałaCollege of Public Health, The Ohio State University, Columbus, OH, USA. rempala.3@osu.edu.

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BEDFORD, TREVOR BC · 2014 to 2018
$12.5M
Regression, Phylogenetics, and Study Design in Infectious Disease EpidemiologyR01AI116770 · NIAID · UNIVERSITY OF FLORIDA · PI KENAH, EBEN · 2016 to 2020
$1.8M
NIAID NIH HHS R01 AI116770NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

The 2018-2020 Ebola virus disease epidemic in Democratic Republic of the Congo (DRC) resulted in 3481 cases (probable and confirmed) and 2299 deaths. In this paper, we use a novel statistical method to analyze the individual-level incidence and hospitalization data on DRC Ebola victims. Our analysis suggests that an increase in the rate of quarantine and isolation that has shortened the infectiousness period by approximately one day during the epidemic's third and final wave was likely responsible for the eventual containment of the outbreak. The analysis further reveals that the total effective population size or the average number of individuals at risk for the disease exposure in three epidemic waves over the period of 24 months was around 16,000-a much smaller number than previously estimated and likely an evidence of at least partial protection of the population at risk through ring vaccination and contact tracing as well as adherence to strict quarantine and isolation policies.

Indexed as

EbolavirusEpidemicsHemorrhagic Fever, EbolaDemocratic Republic of the CongoDisease OutbreaksHumans

Identifiers

PMID35365724
PMCPMC8972744

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.