Evidence map›Paper›PMID 35365472›Full record

ArticleBMJ case reports2022

Ribociclib-induced extensive vitiligo-like lesions: possible pathomechanisms with clinical, dermoscopic and histological correlation.

Gopikrishnan Anjaneyan, Pavithran Keechilat, Prasanna Duraisamy, Malini Eapen

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Survey of Drugs Induced Skin Pigmentation (Hyper and Hypo Pigmentation).Clinical, cosmetic and investigational dermatology · 2025
    Article
  5. Article
  6. Article
  7. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gopikrishnan AnjaneyanDepartment of Dermatology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India drgopikrishnana@gmail.com.ORCID http://orcid.org/0000-0002-3798-1207
Pavithran KeechilatMedical Oncology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India.
Prasanna DuraisamyDepartment of Dermatology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India.ORCID http://orcid.org/0000-0001-8133-8799
Malini EapenDepartment of Pathology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India.
Amrita Institute of Medical Sciences and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclin dependent kinase (CDK) 4/6 inhibitors are targeted agents which act on cyclin-D and these combined with hormonal therapy have been approved for the treatment of locally advanced or metastatic breast cancer. CDK 4/6 inhibitors have been found to have a tolerable adverse event profile; however, they have been associated with various dermatological adverse events. We report a case of ribociclib-induced vitiligo and discuss the clinical, dermoscopic and histological features with a review of the various possible pathomechanisms involved.

Indexed as

VitiligoAminopyridinesCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6HumansProtein Kinase InhibitorsPurinesAminopyridinesCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Protein Kinase InhibitorsPurinesribociclibBreast cancerChemotherapyDermatologyDrugs and medicinesOncology

Identifiers

PMID35365472
PMCPMC8977742
OpenAlexW4221117546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.