Evidence map›Paper›PMID 35365149›Full record

ArticleEnvironmental health : a global access science source2022

Symptoms and functional limitations related to respiratory health and carbon monoxide poisoning in Tanzania: a cross sectional study.

Thomas Zoller, Elirehema H Mfinanga, Tresphory B Zumba, Peter J Asilia, Edwin M Mutabazi, David Wimmersberger, Francis Mhimbira, Frederick Haraka, Klaus Reither

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Thomas ZollerSwiss Tropical and Public Health Institute, Socinstr. 57, 4051, Basel, Switzerland.
Elirehema H MfinangaIfakara Health Institute, Dar es Salaam, Tanzania.
Tresphory B ZumbaIfakara Health Institute, Dar es Salaam, Tanzania.
Peter J AsiliaIfakara Health Institute, Dar es Salaam, Tanzania.
Edwin M MutabaziIfakara Health Institute, Dar es Salaam, Tanzania.
David WimmersbergerSwiss Tropical and Public Health Institute, Socinstr. 57, 4051, Basel, Switzerland.
Francis MhimbiraIfakara Health Institute, Dar es Salaam, Tanzania.
Frederick HarakaSwiss Tropical and Public Health Institute, Socinstr. 57, 4051, Basel, Switzerland.
Klaus ReitherSwiss Tropical and Public Health Institute, Socinstr. 57, 4051, Basel, Switzerland. klaus.reither@swisstph.ch.ORCID 0000-0001-6195-8237
Ifakara Health Institute · TZSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe burden of chronic respiratory symptoms and respiratory functional limitations is underestimated in Africa. Few data are available on carbon monoxide (CO) poisoning in sub-Saharan Africa and existing data is derived from CO in ambient air, but not from biomarkers in the blood.

methodsData from the Tanzanian Lung Health study, a cross-sectional study on lung health among outpatients and visitors to an urban as well as a rural hospital in Tanzania, was analyzed to describe respiratory symptoms and functional limitations. Saturation of peripheral blood with carbon monoxide (SpCO) was measured transcutaneously and non-invasively in participants using a modified pulse oxymeter indicative of CO poisoning. Univariate and multivariate analysis was performed.

resultsNine hundred and ninety-seven participants were included in the analysis, the median age of participants was 46 years (49% male). 38% of participants reported some degree of chronic shortness of breath and 26% felt limited in their daily activities or at work by this symptom. The median SpCO was 7% (IQR 4-13, range 2-31%) among all participants without active smoking status (N = 808). Participants cooking with gas or electricity had the lowest SpCO (median 5%), followed by participants cooking with charcoal (median 7%). Cooking with wood, particularly using a stove, resulted in highest SpCO (median 11.5%). Participants from households where cooking takes place in a separate room had the lowest SpCO as compared to cooking outside or cooking in a shared room inside (6% vs. 9% vs.10.5%, p < 0.01). Sex or the activity of cooking itself was not associated with a difference in SpCO. Multivariate analysis confirmed cooking in a separate room (as compared to cooking outside) and living in a rural vs. urban setting as protective factors against high SpCO.

conclusionThe findings demonstrate a high burden of chronic respiratory symptoms which also cause socioeconomic impact. High levels of SpCO indicate a relevant burden of carbon monoxide poisoning in the local population. The level of CO in the blood is more dependent on shared exposure to sources of CO with the type of housing and type of cooking fuel as most relevant factors, and less on person-individual risk factors or activities.

Indexed as

Carbon Monoxide PoisoningCarbon MonoxideCookingCross-Sectional StudiesFemaleHumansMaleMiddle AgedTanzaniaCarbon MonoxideCarboxyhaemoglobinRespiratory symptomsTanzania

Identifiers

PMID35365149
PMCPMC8976359
OpenAlexW4226125301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.