Evidence map›Paper›PMID 35365063›Full record

Trial reportThe International journal of artificial organs2022

Derivation and validation of the bridge to transplantation with left ventricular assist device score for 1 year mortality after heart transplantation. The BTT-LVAD score.

Alexis K Okoh, Setri Fugar, Sheriff Dodoo, Mariam Selevany, Nawar Al-Obaidi, Ebru Ozturk, Swaiman Singh, Rajiv Tayal, Leonard Y Lee, Mark J Russo and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexis K OkohDivision of Cardiology, Emory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, GA, USA.
Setri FugarDivision of Cardiology, Rush University Medical Center, Chicago, IL, USA.
Sheriff DodooDepartment of Medicine, Piedmont Newnan Hospital, Newnan, GA, USA.ORCID https://orcid.org/0000-0003-3891-5073
Mariam SelevanyCardiovascular Research Unit, RWJBarnabas Health, Newark Beth Israel Medical Center, Newark, NJ, USA.
Nawar Al-ObaidiCardiovascular Research Unit, RWJBarnabas Health, Newark Beth Israel Medical Center, Newark, NJ, USA.
Ebru OzturkDivision of Biostatistics, Hacettepe University School of Medicine, Ankara, Turkey.
Swaiman SinghCardiovascular Research Unit, RWJBarnabas Health, Newark Beth Israel Medical Center, Newark, NJ, USA.
Rajiv TayalCardiovascular Research Unit, RWJBarnabas Health, Newark Beth Israel Medical Center, Newark, NJ, USA.
Leonard Y LeeDivision of Cardiothoracic Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Mark J RussoDivision of Cardiothoracic Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Margarita CamachoCardiovascular Research Unit, RWJBarnabas Health, Newark Beth Israel Medical Center, Newark, NJ, USA.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
Multidisciplinary Research Training to Reduce Inequities in Cardiovascular HealthT32HL130025 · NHLBI · EMORY UNIVERSITY · PI Tené T Lewis, Viola Vaccarino · 2016 to 2026
$6.4M
NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378NHLBI NIH HHS T32 HL130025
6 · The paper itself

Abstract

backgroundTo derive and validate a risk score that accurately predicts 1-year mortality after heart transplantation (HT) in patients bridged to transplant (BTT) with a left ventricular assist device (LVAD).

methodsThe UNOS database was queried to identify patients BTT with an LVAD between 2008 and 2018. Patients with ⩾1-year follow up were randomly divided into derivation (70%) and validation (30%) cohorts. The primary endpoint was 1-year mortality. A simple additive risk score was developed based on the odds of 1-year mortality after HT. Risk groups were created, and survival was estimated and compared.

resultsA total of 7759 patients were randomly assigned to derivation (

conclusionThe BTT-LVAD Score can serve as a clinical decision tool to guide therapeutic decisions in advanced heart failure patients.

Indexed as

Heart-Assist DevicesHeart FailureHeart TransplantationHumansRetrospective StudiesRisk FactorsTreatment Outcomeapheresis and detoxification techniquesartificial kidneycardiac assist and artificial heartcomputational methodscomputer simulationmodeling cardiovascularVentricular assist devices

Identifiers

PMID35365063
PMCPMC10024971

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.