Evidence map›Paper›PMID 35364308›Full record

ArticleComputers in biology and medicine2022

Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (M

Şevki Adem, Volkan Eyupoglu, Ibrahim M Ibrahim, Iqra Sarfraz, Azhar Rasul, Muhammad Ali, Abdo A Elfiky

Open access · greenAbstract read
In one paragraph

Article in Computers in biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
  2. InBiochemistry and biophysics reports · 2024
    Article
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  5. Article
  6. Article
  7. Article
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  10. Article
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  12. Article
  13. Article
  14. In Silico Models for Anti-COVID-19 Drug Discovery: A Systematic Review.Advances in pharmacological and pharmaceutical sciences · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Exploring new catechin derivatives as SARS-CoV-2 MComputers in biology and medicine · 2022
    Article
  19. Review
  20. Antiviral activity of medicinal plant-derived products against SARS-CoV-2.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Şevki AdemDepartment of Chemistry, Faculty of Science, Cankiri Karatekin University, 18100, Cankırı, Turkey.
Volkan EyupogluDepartment of Chemistry, Faculty of Science, Cankiri Karatekin University, 18100, Cankırı, Turkey. Electronic address: volkan@karatekin.edu.tr.
Ibrahim M IbrahimBiophysics Department, Faculty of Science, Cairo University, Giza, Egypt.
Iqra SarfrazCell and Molecular Biology Lab, Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.
Azhar RasulCell and Molecular Biology Lab, Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan. Electronic address: drazharrasul@gmail.com.
Muhammad AliVice Chancellor, Quaid-i-Azam University, Islamabad, Pakistan.
Abdo A ElfikyBiophysics Department, Faculty of Science, Cairo University, Giza, Egypt. Electronic address: abdo@sci.cu.edu.eg.
Cairo University · EGÇankırı Karatekin University · TRGovernment College University, Faisalabad · PKQuaid-i-Azam University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2, a rapidly spreading new strain of human coronavirus, has affected almost all the countries around the world. The lack of specific drugs against SARS-CoV-2 is a significant hurdle towards the successful treatment of COVID-19. Thus, there is an urgent need to boost up research for the development of effective therapeutics against COVID-19. In the current study, we investigated the efficacy of 81 medicinal plant-based bioactive compounds against SARS-CoV-2 M

Indexed as

COVID-19 Drug TreatmentCoronavirus 3C ProteasesHumansMolecular Docking SimulationMolecular Dynamics SimulationPolyphenolsProtease InhibitorsSARS-CoV-23C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesPolyphenolsProtease InhibitorsCOVID-19FlavonoidsMolecular dockingMolecular dynamics simulationQuantum mechanicSARS CoV-2 M(pro)

Identifiers

PMID35364308
PMCPMC8957318
OpenAlexW4220916418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.