ArticleThe Journal of heredity2022
Chromosome-Level Genome Assembly Reveals Dynamic Sex Chromosomes in Neotropical Leaf-Litter Geckos (Sphaerodactylidae: Sphaerodactylus).
Article in The Journal of heredity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A lizard is never late: Squamate genomics as a recent catalyst for understanding sex chromosome and microchromosome evolution.The Journal of heredity · 2023Pooled it
- Sex chromosome identification and genome curation from a single individual with SCINKD.Molecular biology and evolution · 2026Article
- Unravelling the thread of Podarcis omics; insights into the genome and transcriptome of the Cretan wall lizard.Genes & genomics · 2026Article
- Chromosome-level genome assembly of Turpan wonder gecko (Teratoscincus roborowskii) reveals olfactory candidate genes.Scientific data · 2025Article
- The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes.Journal of evolutionary biology · 2025Article
- Genomes of two Extinct-in-the-Wild reptiles from Christmas Island reveal distinct evolutionary histories and conservation insights.Molecular ecology resources · 2025Article
- High-quality genome assembly and annotation of the crested gecko (Correlophus ciliatus).G3 (Bethesda, Md.) · 2025Article
- Tokay gecko tail regeneration involves temporally collinear expression of HOXC genes and early expression of satellite cell markers.BMC biology · 2025Article
- Article
- Sex chromosome cycle as a mechanism of stable sex determination.Journal of biochemistry · 2024Review
- Diversity of Sex Chromosomes in Vertebrates: Six Novel Sex Chromosomes in Basal Haplochromines (Teleostei: Cichlidae).Genome biology and evolution · 2024Article
- Lack of Dosage Balance and Incomplete Dosage Compensation in the ZZ/ZW Gila Monster (Heloderma suspectum) Revealed by De Novo Genome Assembly.Genome biology and evolution · 2024Article
- It's a trap?! Escape from an ancient, ancestral sex chromosome system and implication of Foxl2 as the putative primary sex-determining gene in a lizard (Anguimorpha; Shinisauridae).Evolution; international journal of organic evolution · 2024Article
- Chromosome-level genome assembly and annotation of the crested gecko,GigaByte (Hong Kong, China) · 2024Article
- It's a Trap?! Escape from an ancient, ancestral sex chromosome system and implication ofbioRxiv : the preprint server for biology · 2023Article
- The revised reference genome of the leopard gecko (Eublepharis macularius) provides insight into the considerations of genome phasing and assembly.The Journal of heredity · 2023Article
- Review
- Incomplete dosage balance and dosage compensation in the ZZ/ZW Gila monster (bioRxiv : the preprint server for biology · 2023Article
- A lizard is never late: squamate genomics as a recent catalyst for understanding sex chromosome and microchromosome evolution.bioRxiv : the preprint server for biology · 2023Article
- The revised reference genome of the leopard gecko (bioRxiv : the preprint server for biology · 2023Article
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Authors and funding
6 authors.
Funding
Abstract
Sex determination is a critical element of successful vertebrate development, suggesting that sex chromosome systems might be evolutionarily stable across lineages. For example, mammals and birds have maintained conserved sex chromosome systems over long evolutionary time periods. Other vertebrates, in contrast, have undergone frequent sex chromosome transitions, which is even more amazing considering we still know comparatively little across large swaths of their respective phylogenies. One reptile group in particular, the gecko lizards (infraorder Gekkota), shows an exceptional lability with regard to sex chromosome transitions and may possess the majority of transitions within squamates (lizards and snakes). However, detailed genomic and cytogenetic information about sex chromosomes is lacking for most gecko species, leaving large gaps in our understanding of the evolutionary processes at play. To address this, we assembled a chromosome-level genome for a gecko (Sphaerodactylidae: Sphaerodactylus) and used this assembly to search for sex chromosomes among six closely related species using a variety of genomic data, including whole-genome re-sequencing, RADseq, and RNAseq. Previous work has identified XY systems in two species of Sphaerodactylus geckos. We expand upon that work to identify between two and four sex chromosome cis-transitions (XY to a new XY) within the genus. Interestingly, we confirmed two different linkage groups as XY sex chromosome systems that were previously unknown to act as sex chromosomes in tetrapods (syntenic with Gallus chromosome 3 and Gallus chromosomes 18/30/33), further highlighting a unique and fascinating trend that most linkage groups have the potential to act as sex chromosomes in squamates.
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