Evidence map›Paper›PMID 35363529›Full record

ArticleScience advances2022

Genetic elimination of rod/cone coupling reveals the contribution of the secondary rod pathway to the retinal output.

Nange Jin, Lian-Ming Tian, Iris Fahrenfort, Zhijing Zhang, Friso Postma, David L Paul, Stephen C Massey, Christophe P Ribelayga

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Stephen Massey: a career in visual neuroscience.Frontiers in ophthalmology · 2023
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nange JinRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA.ORCID 0000-0002-3600-8376
Lian-Ming TianRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA.
Iris FahrenfortRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA.ORCID 0000-0002-1501-8858
Zhijing ZhangRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA.
Friso PostmaDepartment of Neurobiology, Medical School, Harvard University, Boston, MA, USA.ORCID 0000-0003-4453-5392
David L PaulDepartment of Neurobiology, Medical School, Harvard University, Boston, MA, USA.ORCID 0000-0002-8742-525X
Stephen C MasseyRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA.ORCID 0000-0003-0224-6031
Christophe P RibelaygaRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston), Houston, TX, USA.ORCID 0000-0001-5889-2070
The University of Texas Health Science Center · USHarvard University · US

Funding

UTHouston Core Center for Vision ResearchP30EY028102 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DRAGOI, VALENTIN · 2017 to 2021
$3.1M
Rod/cone gap junctions initiate an irradiance pathwayR01EY029408 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MASSEY, STEPHEN C, RIBELAYGA, CHRISTOPHE P. · 2018 to 2022
$2.9M
Plasticity and Function of the Rod/Cone Gap JunctionR01EY032508 · NEI · UNIVERSITY OF HOUSTON · PI Christophe P. Ribelayga · 2022 to 2026
$2.4M
Strategy to map electrical synaptic connectivity in neural networksRF1MH127343 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI AICHER, SUE A, MASSEY, STEPHEN C · 2021 to 2021
$1.8M
NEI NIH HHS P30 EY028102NEI NIH HHS R01 EY029408NEI NIH HHS R01 EY032508NIMH NIH HHS RF1 MH127343
6 · The paper itself

Abstract

In the retina, signals originating from rod and cone photoreceptors can reach retinal ganglion cells (RGCs)-the output neurons-through different pathways. However, little is known about the exact sensitivities and operating ranges of these pathways. Previously, we created rod- or cone-specific

Identifiers

PMID35363529
PMCPMC10938630
OpenAlexW4220667000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.