Evidence map›Paper›PMID 35363133›Full record

ArticleSICOT-J2022

Outcomes of double level osteotomy for osteoarthritic knees with severe varus deformity. A systematic review.

Hany Elbardesy, André McLeod, Hazem S Ghaith, Samir Hakeem, Philip Housden

Registry-linked trialAbstract read
In one paragraph

Article in SICOT-J, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07283237 (Enhancing Medial Knee Pain Rehabilitation), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07283237 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Enhancing Medial Knee Pain Rehabilitation : A Clinical Trial On The Effectiveness Of Blood Flow Restriction In Combination With Targeted Exercises For Adult With Varus Deformity

TypeinterventionalSponsorAssiut UniversityRan2025 to 2026Enrolled80ConditionsKnee Osteoarthritis (Mild to Moderate, Medial Compartment)ArmsTargeted Exercise Program, Blood Flow Restriction (BFR) Training with Targeted Exercise Program
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  3. Mid-term survival and physiological joint angles after double level osteotomy of severe varus osteoarthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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  12. The joint line convergence angle (JLCA) correlates with intra-articular arthritis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hany ElbardesyDepartment of Trauma and Orthopaedics, East Kent University Hospital, Kent TN240LY, UK.ORCID 0000-0001-8600-6339
André McLeodOrthopaedic Senior House Officer, Department of Trauma and Orthopaedic Surgery, Cork University Hospital, Wilton, Cork T12DC4A, Ireland.ORCID 0000-0002-5318-2181
Hazem S GhaithFaculty of Medicine, Al-Azhar University, Cairo 11651, Egypt.ORCID 0000-0002-9519-851X
Samir HakeemOrthopaedic Registrar, Department of Trauma and Orthopaedic, Galway University Hospital, Galway H91 YR71, Ireland.ORCID 0000-0002-4866-7424
Philip HousdenDepartment of Trauma and Orthopaedics, East Kent University Hospital, Kent TN240LY, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen correcting severe genu varus deformity, knee surgeons must choose between performing a single or double-level osteotomy. This systematic review aims to provide this equipoise with some clarity. PATIENTS AND

methodsWe conducted this study following the Preferred Reporting Items for Systematic Reviews and Meta-analyses Statement (PRISMA) and the Cochrane Handbook for systematic reviews and meta-analysis. Studies evaluating the effect of the double level osteotomy (DLO) or those comparing it to high tibial osteotomy (HTO) from all regions and written in any language were included.

resultsSix studies were included in this systematic review. They were prepared and analysed using Review Manager V5.0 [Computer Program] (RevMan5). Performing DLO resulted in restoring patellar height, joint-line convergence angle (JLCA), and mMPTA to normal values. DLO was also more successful at avoiding joint line obliquity (JLO) in severe varus deformity when compared to HTO (P < 0.001). No significant difference was reported between the two cohorts regarding the mLPTA. DLO resulted in satisfactory short term KOOS and IKDC scores. The complication rate after DLO was 2.28%.

conclusionsDLO showed a low complication rate and satisfactory short term KOOS and IKDAC scores. Randomised control trials with long term follow-up comparing the DLO and HTO are recommended.

Indexed as

Double level osteotomyKneeOsteoarthritisOsteotomyVarus knee

Identifiers

PMID35363133
PMCPMC8973300

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.