Evidence map›Paper›PMID 35362883›Full record

ReviewEnvironmental science and pollution research international2022

Targeting natural products against SARS-CoV-2.

Ahmed Al-Harrasi, Tapan Behl, Tanuj Upadhyay, Sridevi Chigurupati, Shvetank Bhatt, Aayush Sehgal, Saurabh Bhatia, Sukhbir Singh, Neelam Sharma, Shantini Vijayabalan and 5 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Discovery of Polyphenolic Natural Products as SARS-CoV-2 MPharmaceuticals (Basel, Switzerland) · 2023
    Article
  9. Molecular docking study of variousFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 6 countries.

Ahmed Al-HarrasiNatural & Medical Sciences Research Center, University of Nizwa, Birkat Al Mawz, Oman.
Tapan BehlChitkara College of Pharmacy, Chitkara University, Punjab, India. tapanbehl31@gmail.com.ORCID http://orcid.org/0000-0003-0993-7708
Tanuj UpadhyayAmity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India.
Sridevi ChigurupatiDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraidah, Kingdom of Saudi Arabia.
Shvetank BhattAmity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India.
Aayush SehgalChitkara College of Pharmacy, Chitkara University, Punjab, India.
Saurabh BhatiaNatural & Medical Sciences Research Center, University of Nizwa, Birkat Al Mawz, Oman.
Sukhbir SinghChitkara College of Pharmacy, Chitkara University, Punjab, India.
Neelam SharmaChitkara College of Pharmacy, Chitkara University, Punjab, India.
Shantini VijayabalanFaculty of Health and Medical Sciences, School of Pharmacy, Taylor's University, Subang Jaya, Kuala Lumpur, Malaysia.
Vasanth Raj PalanimuthuDepartment of Pharmaceutical Biotechnology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamilnadu, India.
Suprava DasDepartment of Pharmacology, Faculty of Medicine, AIMST University, Semeling, Bedong, Kedah, Malaysia.
Rajwinder KaurChitkara College of Pharmacy, Chitkara University, Punjab, India.
Lotfi AleyaChrono-Environment Laboratory, UMR CNRS 6249, Bourgogne Franche-Comté University, Besançon, France.
Simona BungauDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Chitkara University · INUniversity of Nizwa · OMAIMST University · MYCentre National de la Recherche Scientifique · FRJSS Academy of Higher Education and Research · INQassim University · SATaylor's University · MYUniversity of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human coronavirus disease (COVID-19) pandemic is caused by a novel coronavirus; the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Natural products, secondary metabolites show positive leads with antiviral and immunotherapy treatments using genomic studies in silico docking. In addition, it includes the action of a mechanism targeting the SARS-CoV-2. In this literature, we aimed to evaluate the antiviral movement of the NT-VRL-1 unique terpene definition to Human coronavirus (HCoV-229E). The effects of 19 hydrolysable tannins on the SARS-CoV-2 were therefore theoretically reviewed and analyzed utilising the molecular operating surroundings for their C-Like protease 3CLpro catalytic dyad residues Angiotensin converting enzyme-2 (MOE 09). Pedunculagin, tercatan, and castalin were detected as interacting strongly with SARS-receptor Cov-2's binding site and catalytic dyad (Cys145 and His41). SARS-CoV-2 methods of subunit S1 (ACE2) inhibit the interaction of the receiver with the s-protein once a drug molecule is coupled to the s-protein and prevent it from infecting the target cells in alkaloids. Our review strongly demonstrates the evidence that natural compounds and their derivatives can be used against the human coronavirus and serves as an area of research for future perspective.

Indexed as

Biological ProductsCOVID-19Antiviral AgentsHumansPandemicsSARS-CoV-2Antiviral AgentsBiological ProductsCOVID-19Human coronavirusNatural productsSevere acute respiratory syndrome

Identifiers

PMID35362883
PMCPMC8972763
OpenAlexW4220956719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.