ArticleIntensive care medicine2022
Trends and risk factors for omission of early thromboprophylaxis in Australian and New Zealand ICUs between 2009 and 2020.
Article in Intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Risk factors of venous thromboembolism in ICU patients: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- Knowledge, attitudes, and practices of patients with multiple myeloma regarding venous thromboembolism: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Machine Learning-Based Early Prediction of Lower Extremity Deep Vein Thrombosis in the ICU: A Multicenter Study.Risk management and healthcare policy · 2026Article
- The impact of the CERTAIN clinical decision support tool for structured intensive care unit admission and rounding is patient sex-independent: a secondary analysis of CERTAIN.Critical care science · 2025Article
- Venous thromboembolism in critically ill adult patients with hematologic malignancy: a population-based cohort study.Intensive care medicine · 2024Article
- Mortality data from omission of early thromboprophylaxis in critically ill patients highlights the importance of an individualised diagnosis-related approach.Thrombosis journal · 2023Article
- The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute a simple solution.Intensive care medicine · 2022Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVenous thromboembolism (VTE) prophylaxis is effective in reducing VTE events; however, it is underutilized in critically ill patients. We examined trends and risk factors for omission of early thromboprophylaxis within the first 24 h after admission in Australian and New Zealand intensive care units (ICUs) between 2009 and 2020.
methodsRetrospective analysis of data from the Australian New Zealand Intensive Care Society Adult Patient Database. Data were obtained for 1,465,020 adult admissions between 2009 and 2020. Mixed effects logistic regression modeling (accounting for the random effects of the contributing ICUs) was used to identify factors associated with omission of early thromboprophylaxis.
resultsA total of 107,486 (7.3%) ICU patients did not receive any form of thromboprophylaxis within the first 24 h after ICU admission without obvious reasons. Omission of early thromboprophylaxis declined from 13.7% in 2009 to 4% in 2020 (by 70.8%) (P < 0.001). Younger patients were more like to miss out on VTE prophylaxis (odds ratios (OR)
conclusionOmission of thromboprophylaxis within the first 24 h after ICU admission has declined steadily over the past decade. Documented process for monitoring VTE prophylaxis and having a medical lead for coordinating quality of ICU care could be potential targets for sustaining the improvement in VTE prophylaxis use.
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