Metformin: A promising option for the management of gestational diabetes mellitus - Exploring the benefits, challenges and clinical needs in the current management of gestational diabetes mellitus.

Beenu Bastian, Lisa Gaye Smithers, Warren Davis, Alexia Pape, Monique E Francois

Open access · hybridAbstract read

In one paragraph

Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

1.1field-weighted citation impact, top 24% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Beenu BastianSchool of Medicine, University of Wollongong, Wollongong, New South Wales, Australia.ORCID 0000-0001-9266-9817

Lisa Gaye SmithersIllawarra Health and Medical Research Institute, Wollongong, New South Wales, Australia.

Warren DavisSchool of Medicine, University of Wollongong, Wollongong, New South Wales, Australia.

Alexia PapeWollongong Hospital, Illawarra Shoalhaven Local Health District, Wollongong, New South Wales, Australia.

Monique E FrancoisSchool of Medicine, University of Wollongong, Wollongong, New South Wales, Australia.

University of Wollongong · AUWollongong Hospital · AU

Funding

NHMRC

6 · The paper itself

Abstract

The incidence of gestational diabetes mellitus (GDM) is increasing. One in three women require insulin to achieve glycaemic targets in GDM. However, it is unclear whether insulin therapy alone is the most effective treatment for all women in achieving glycaemic control and preventing adverse pregnancy outcomes. Although no oral hypoglycaemic agents are approved for pregnancy in Australia, recent research indicates that metformin is effective in preventing adverse perinatal outcomes and may even have possible benefits in the long term. Furthermore, there appears to be a specific role for both metformin and insulin among the GDM population. Metformin provides an option to offer an individualised approach to treat GDM.

Indexed as

Diabetes, GestationalMetforminBlood GlucoseFemaleHumansHypoglycemic AgentsInsulinPregnancyBlood GlucoseHypoglycemic AgentsInsulinMetformingestational diabetes mellitusinsulin, metforminpregnancypregnancy complication

Identifiers

PMID35362563

DOI10.1111/ajo.13513

PMCPMC9542201

OpenAlexW4220829100

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.