Evidence map›Paper›PMID 35362454›Full record

ArticleJournal of neurogastroenterology and motility2022

Self-reported Non-celiac Gluten Sensitivity in the Korean Population: Demographic and Clinical Characteristics.

Ra Ri Cha, Jeong Hwan Kim, Hoon Sup Koo, Kee Wook Jung, Yang Won Min, Chang Hwan Choi, Han Seung Ryu, Yong Hwan Kwon, Dae Hyeon Cho, Joong Goo Kwon and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  7. Non-celiac Gluten Sensitivity or Celiac Disease, This Is Still the Question.Journal of neurogastroenterology and motility · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 1 country.

Ra Ri ChaDepartment of Internal Medicine, Gyeongsang National University School of Medicine Gyeongsang National University Changwon Hospital, Changwon, Gyeongsangnam-do, Korea.
Jeong Hwan KimDepartment of Internal Medicine, Konkuk University Medical Center, Seoul, Korea.
Hoon Sup KooDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Kee Wook JungDepartment of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yang Won MinDepartment of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chang Hwan ChoiDepartment of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Han Seung RyuDepartment of Internal Medicine, Wonkwang University College of Medicine and Digestive Disease Research Institute, Iksan, Jeollabuk-do, Korea.
Yong Hwan KwonDepartment of Internal Medicine, Kyungpook National University School of Medicine Kyungpook National University Hospital, Daegu, Korea.
Dae Hyeon ChoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University of Medicine, Changwon, Gyeongsangnam-do, Korea.
Joong Goo KwonDepartment of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
Kyung Sik ParkDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Hyun Jin KimDepartment of Internal Medicine, Gyeongsang National University School of Medicine Gyeongsang National University Changwon Hospital, Changwon, Gyeongsangnam-do, Korea.
Sungkyunkwan University · KRAsan Medical Center · KRCatholic University of Daegu · KRChangwon National University · KRChung-Ang University · KRGyeongsang National University · KRKeimyung University · KRKonkuk University Medical Center · KRKonyang University · KRKyungpook National University Hospital · KRWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Non-celiac gluten sensitivity is characterized by intestinal and extra intestinal symptoms associated with the consumption of gluten-containing food. Since biomarkers for non-celiac gluten sensitivity are lacking, its prevalence is estimated based on self-reported symptoms. However, no data exist on self-reported non-celiac gluten sensitivity in the Korean population. Thus, we aim to investigate the prevalence of self-reported non-celiac gluten sensitivity in the Korean population and to determine its demographic and clinical characteristics. Methods: This study surveyed Korean participants aged 18-80 years who visited gastroenterology outpatient clinics at 9 tertiary hospitals in South Korea from January 2016 to February 2017. They were questioned regarding symptoms related to gluten ingestion: degree of discomfort (visual analog scale score), frequency, time of symptom onset, and duration. Abdominal discomfort caused by 11 different kinds of gluten-containing Korean food items was investigated. Results: More non-celiac gluten sensitivity self-reporters were identified among those with irritable bowel syndrome (33.6%) than among controls (5.8%). Major gastrointestinal symptoms included bloating (75.0%), abdominal discomfort (71.3%), and belching (45.0%). Common extra-intestinal symptoms included fatigue (20.0%) and headache (13.7%). More than half of those who self-reported non-celiac gluten sensitivity (66.3%) developed symptoms within 1 hour of food ingestion, and symptoms were localized in the upper abdomen (37.5%) and entire abdomen (30.0%). Conclusion: Our findings suggest that if there are gluten-related symptoms in irritable bowel syndrome, the possibility of accompanying non-celiac gluten sensitivity should be considered.

Indexed as

Celiac diseaseGastrointestinal diseasesKoreaWheat hypersensitivity

Identifiers

PMID35362454
PMCPMC8978116
OpenAlexW4220944984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.