Evidence map›Paper›PMID 35361822›Full record

ArticleScientific reports2022

Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv.

Merve Arslan, Murat Karadag, Ebru Onal, Emine Gelinci, Gulcin Cakan-Akdogan, Sibel Kalyoncu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  3. P450 Fusion Protein Expressed inMolecules (Basel, Switzerland) · 2026
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  12. Cytoplasmic ribosomes hitchhike on mitochondria to dendrites.bioRxiv : the preprint server for biology · 2024
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Merve ArslanIzmir Biomedicine and Genome Center, Izmir, Turkey.
Murat KaradagIzmir Biomedicine and Genome Center, Izmir, Turkey.
Ebru OnalIzmir Biomedicine and Genome Center, Izmir, Turkey.
Emine GelinciIzmir Biomedicine and Genome Center, Izmir, Turkey.
Gulcin Cakan-AkdoganIzmir Biomedicine and Genome Center, Izmir, Turkey.
Sibel KalyoncuIzmir Biomedicine and Genome Center, Izmir, Turkey. sibel.kalyoncu@ibg.edu.tr.
Izmir University · TRDokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single chain antibody fragments (scFvs) are favored in diagnostic and therapeutic fields thanks to their small size and the availability of various engineering approaches. Linker between variable heavy (V

Indexed as

Immunoglobulin Variable RegionZebrafishAnimalsAntibodies, MonoclonalImmunoglobulin FragmentsVascular Endothelial Growth FactorsAntibodies, MonoclonalImmunoglobulin FragmentsImmunoglobulin Variable RegionVascular Endothelial Growth Factors

Identifiers

PMID35361822
PMCPMC8971466
OpenAlexW4220856854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.