Evidence map›Paper›PMID 35361789›Full record

ArticleNature communications2022

Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination.

Vijaykrishna Dhanasekaran, Sheena Sullivan, Kimberly M Edwards, Ruopeng Xie, Arseniy Khvorov, Sophie A Valkenburg, Benjamin J Cowling, Ian G Barr

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 4 pooled it
36.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 4 syntheses or guidelines pooled it, 240 citations in OpenAlex.

  1. Pooled it
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  3. Comparisons in the Health and Economic Assessments of Using Quadrivalent Versus Trivalent Influenza Vaccines: A Systematic Literature Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2023
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  17. Global influenza epidemiology after 2020: patterns of circulation, epidemic timing and duration, and implications for vaccination strategies.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
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  19. Review
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Vijaykrishna DhanasekaranSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. veej@hku.hk.ORCID http://orcid.org/0000-0003-3293-6279
Sheena SullivanWHO Collaborating Centre for Reference and Research on Influenza, VIDRL, Peter Doherty Institute for Infection and Immunity, 3000, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-0856-0294
Kimberly M EdwardsSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0003-0944-3118
Ruopeng XieSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Arseniy KhvorovWHO Collaborating Centre for Reference and Research on Influenza, VIDRL, Peter Doherty Institute for Infection and Immunity, 3000, Melbourne, VIC, Australia.
Sophie A ValkenburgSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0002-0768-9926
Benjamin J CowlingSchool of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0002-6297-7154
Ian G BarrWHO Collaborating Centre for Reference and Research on Influenza, VIDRL, Peter Doherty Institute for Infection and Immunity, 3000, Melbourne, VIC, Australia.
HKU-Pasteur Research Pole · HKVictorian Infectious Diseases Reference Laboratory · AUThe University of Melbourne · AUUniversity of Hong Kong · HK

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4M
NIAID NIH HHS 75N93021C00016NIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

Annual epidemics of seasonal influenza cause hundreds of thousands of deaths, high levels of morbidity, and substantial economic loss. Yet, global influenza circulation has been heavily suppressed by public health measures and travel restrictions since the onset of the COVID-19 pandemic. Notably, the influenza B/Yamagata lineage has not been conclusively detected since April 2020, and A(H3N2), A(H1N1), and B/Victoria viruses have since circulated with considerably less genetic diversity. Travel restrictions have largely confined regional outbreaks of A(H3N2) to South and Southeast Asia, B/Victoria to China, and A(H1N1) to West Africa. Seasonal influenza transmission lineages continue to perish globally, except in these select hotspots, which will likely seed future epidemics. Waning population immunity and sporadic case detection will further challenge influenza vaccine strain selection and epidemic control. We offer a perspective on the potential short- and long-term evolutionary dynamics of seasonal influenza and discuss potential consequences and mitigation strategies as global travel gradually returns to pre-pandemic levels.

Indexed as

COVID-19Influenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesHumansInfluenza A Virus, H3N2 SubtypePandemicsSeasonsInfluenza Vaccines

Identifiers

PMID35361789
PMCPMC8971476
OpenAlexW4225551193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.