Evidence map›Paper›PMID 35361655›Full record

ArticleBMJ open2022

Interventions for physician prescribers of opioids for chronic non-cancer pain: protocol for an overview of systematic reviews.

Erica Wennberg, Sarah B Windle, Kristian B Filion, Genevieve Gore, Brett D Thombs, Irina Kudrina, Elena Paraskevopoulos, Marc O Martel, Jonathan Kimmelman, Sonia Johnson and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Erica WennbergLady Davis Institute for Medical Research, Montreal, Québec, Canada.ORCID 0000-0002-8069-6778
Sarah B WindleLady Davis Institute for Medical Research, Montreal, Québec, Canada.
Kristian B FilionLady Davis Institute for Medical Research, Montreal, Québec, Canada.ORCID 0000-0001-6055-0088
Genevieve GoreSchulich Library of Science and Engineering, McGill University, Montreal, Québec, Canada.
Brett D ThombsLady Davis Institute for Medical Research, Montreal, Québec, Canada.ORCID 0000-0002-5644-8432
Irina KudrinaDepartment of Anesthesia, McGill University, Montreal, Québec, Canada.
Elena ParaskevopoulosDepartment of Family Medicine, Royal Ottawa Mental Health Centre, Ottawa, Ontario, Canada.
Marc O MartelDepartment of Anesthesia, McGill University, Montreal, Québec, Canada.
Jonathan KimmelmanBiomedical Ethics Unit, McGill University, Montreal, Québec, Canada.ORCID 0000-0003-1614-6779
Sonia JohnsonHealth Canada, Ottawa, Ontario, Canada.
Andrew TaylorHealth Canada, Ottawa, Ontario, Canada.
Mark J EisenbergLady Davis Institute for Medical Research, Montreal, Québec, Canada mark.eisenberg@ladydavis.ca.ORCID 0000-0002-1296-0661
Jewish General Hospital · CAMcGill University · CAHealth Canada · CAQueensway-Carleton Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInterventions targeting behaviours of physician prescribers of opioids for chronic non-cancer pain have been introduced to combat the opioid crisis. Systematic reviews have evaluated effects of specific interventions (eg, prescriber education, prescription drug monitoring programmes) on patient and population health outcomes and prescriber behaviour. Integration of findings across intervention types is needed to better understand the effects of prescriber-targeted interventions. METHODS AND ANALYSIS: We will conduct an overview of systematic reviews. Eligible systematic reviews will include primary studies that evaluated any intervention targeting the behaviours of physician prescribers of opioids for chronic non-cancer pain in an outpatient or mixed setting, compared with no intervention, usual practice or another active or control intervention. Eligible outcomes will pertain to the intervention effect on patient and population health or opioid prescribing behaviour. We will search MEDLINE, Embase and PsycInfo via Ovid; the Cochrane Database of Systematic Reviews and Epistemonikos from inception. We will also hand search reference lists for additional publications. Screening and data extraction will be conducted independently by two reviewers, with disagreements resolved by consensus or consultation with a third reviewer. The risk of bias of included systematic reviews will be assessed in duplicate by two reviewers using the Risk of Bias in Systematic Reviews tool. Results will be synthesised narratively by intervention type and grouped by outcome. To assist with result interpretation, outcomes will be labelled as intended or unintended according to intervention objectives, and as positive, negative, evidence of no effect or inconclusive evidence according to effect on the population (for patient and population health outcomes) or intervention objectives (for prescriber outcomes). ETHICS AND DISSEMINATION: As the proposed study will use published data, ethics approval is not required. Dissemination of results will be achieved through publication of a manuscript in a peer-reviewed journal and conference presentations. PROSPERO REGISTRATION NUMBER: CRD42020156815.

Indexed as

Chronic PainPhysiciansAnalgesics, OpioidHumansPractice Patterns, Physicians'Systematic Reviews as TopicAnalgesics, Opioidepidemiologypain managementpublic healthsubstance misuse

Identifiers

PMID35361655
PMCPMC8971769
OpenAlexW4221052040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.