Evidence map›Paper›PMID 35361494›Full record

ArticleGeneral hospital psychiatry

Association of depression and COVID-induced PTSD with cognitive symptoms after COVID-19 illness.

Nadia A Liyanage-Don, Melodie R Winawer, Marla J Hamberger, Sachin Agarwal, Alison R Trainor, Kristal A Quispe, Ian M Kronish

Open access · greenAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nadia A Liyanage-DonCenter for Behavioral Cardiovascular Health, Columbia University Irving Medical Center, USA; Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, USA.
Melodie R WinawerDepartment of Neurology, Columbia University Vagelos College of Physicians and Surgeons, USA.
Marla J HambergerDepartment of Neurology, Columbia University Vagelos College of Physicians and Surgeons, USA.
Sachin AgarwalDepartment of Neurology, Columbia University Vagelos College of Physicians and Surgeons, USA.
Alison R TrainorCenter for Behavioral Cardiovascular Health, Columbia University Irving Medical Center, USA.
Kristal A QuispeCenter for Behavioral Cardiovascular Health, Columbia University Irving Medical Center, USA.
Ian M KronishCenter for Behavioral Cardiovascular Health, Columbia University Irving Medical Center, USA; Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, USA. Electronic address: ik2293@cumc.columbia.edu.
Columbia University Irving Medical Center · USColumbia University · US

Funding

Roybal Center for Fearless Behavior Change - renewal Behavioral Intervention Development (BID) CoreP30AG064198 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nathalie Moise · 2019 to 2026
$7.4M
Impact of Social-Interpersonal Factors in the ER on PTSD/Cardiac OutcomesR01HL117832 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., EDMONDSON, DONALD · 2013 to 2017
$3.1M
Impact of PTSD on cardiovascular risk in survivors of stroke and transient ischemic attackR01HL132347 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDMONDSON, DONALD, KRONISH, IAN MATTHEW · 2016 to 2019
$3.1M
Test of a new theory to explain excess risk in cardiac PTSDR01HL128310 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDMONDSON, DONALD · 2015 to 2018
$2.6M
PTSD, Medication Adherence, and Prognosis after Acute Coronary SyndromesR01HL123368 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., KRONISH, IAN MATTHEW · 2014 to 2017
$1.6M
NHLBI NIH HHS R01 HL117832NHLBI NIH HHS R01 HL123368NHLBI NIH HHS R01 HL128310NHLBI NIH HHS R01 HL132347NIA NIH HHS P30 AG064198
6 · The paper itself

Abstract

objectiveMany patients recovering from COVID-19 report persistent psychological and cognitive symptoms months after viral clearance. We examined the association of depression and COVID-induced PTSD with cognitive symptoms following COVID-19 illness.

methodsPatients treated for COVID-19 between March 26 and May 27, 2020 were surveyed three months later. Cognitive symptoms were assessed by asking "Since your COVID-19 illness, do you now have more difficulty: 1) Remembering conversations a few days later? 2) Remembering where you placed familiar objects? 3) Finding the right words while speaking?" Patients endorsing at least one such complaint were coded positive for cognitive symptoms. Logistic regression was used to estimate the association of depression (PHQ-8 ≥ 10) and COVID-induced PTSD (PCL-5 ≥ 30) with cognitive symptoms, adjusting for demographic and clinical factors.

resultsAmong 153 participants, 44.4% reported at least one cognitive symptom, 18.3% were depressed, and 23.5% had COVID-induced PTSD. Adjusting for covariates, depression (OR 5.15, 95% CI 1.30-20.35, p = 0.02) and COVID-induced PTSD (OR 3.67, 95% CI 1.13-11.89, p = 0.03) were significantly associated with cognitive symptoms; self-reported history of mental illness was also associated (OR 4.90, 95% CI 1.24-19.41, p = 0.02).

conclusionsDepression, COVID-induced PTSD, and prior mental illness were strongly associated with cognitive symptoms three months after acute COVID-19 illness.

Indexed as

COVID-19Stress Disorders, Post-TraumaticCognitionDepressionHumansSurveys and QuestionnairesCognitive symptomsCOVID-19 illnessDepressionPost-traumatic stress disorder (PTSD)

Identifiers

PMID35361494
PMCPMC8889792
OpenAlexW4214858459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.