ReviewGastrointestinal endoscopy clinics of North America2022
Cause, Epidemiology, and Histology of Polyps and Pathways to Colorectal Cancer.
Review in Gastrointestinal endoscopy clinics of North America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 4 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Pooled it
- AGA Living Clinical Practice Guideline on Computer-Aided Detection-Assisted Colonoscopy.Gastroenterology · 2025Guideline
- ESR Essentials: Imaging in colorectal cancer-practice recommendations by ESGAR.European radiology · 2024Guideline
- Pooled it
- CT-based radiogenomic analysis to predict high-risk colon cancer (ATTRACT): a multicentric trial.European radiology · 2025Trial
- Evaluation efficacy and accuracy of a real-time computer-aided polyp detection system during colonoscopy: a prospective, multicentric, randomized, parallel-controlled study trial.Surgical endoscopy · 2025Trial
- Application of colonoscopic auxiliary devices in reducing the polyp miss rate: a prospective randomized controlled study.BMC gastroenterology · 2025Trial
- Adverse events after colonoscopy in a randomised colorectal cancer screening trial.BMJ open gastroenterology · 2024Trial
- Outcomes of 'in-house' genetic testing within a specialist hereditary colorectal cancer registry.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- KRAS in Colorectal Cancer: Tumorigenesis, Surgical Implications and Evolving Treatment Target.Current oncology (Toronto, Ont.) · 2026Review
- See more, detect more: investigating colonic inspection techniques and polyp detection using machine learning.Surgical endoscopy · 2026Article
- Mutational landscape in the precancerous stages of sporadic colorectal cancer.Oncology letters · 2026Article
- Integrative omics identify NID2 as a therapeutic target linking depression and colorectal cancer in humans.iScience · 2026Article
- Design and implementation of an end-to-end AI-driven colonoscopy recall workflow at scale.JAMIA open · 2026Article
- Serum Exosomal Hsa_circ_0005692 as A Novel Biomarker for Colorectal Cancer Metastasis: A Retrospective Observational Study.Applied biochemistry and biotechnology · 2026Observational
- Colibactin-associated mutations in the human colon appear to reflect anatomy and early exposure, not oncogenesis.medRxiv : the preprint server for health sciences · 2026Article
- Future Perspectives: Mass Spectrometry for Spatial Localisation of Anti-Angiogenic Oil Palm Compounds.International journal of molecular sciences · 2026Review
- Investigation of the relationship between helicobacter pylori positivity and colon polyps in simultaneous oesophagogastroduodenoscopy and colonoscopy procedures.Journal of minimal access surgery · 2026Article
- Impact of sedation on adenoma and polyp detection rates and cecal intubation in elderly patients undergoing screening colonoscopy.World journal of gastrointestinal pharmacology and therapeutics · 2026Article
- Endoscopic characterization and development of a prediction model for colorectal adenomatous polyps.World journal of gastrointestinal surgery · 2026Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Colorectal cancer is the second leading cause of cancer-associated mortality, with a lifetime risk of approximately 4% to 5%. Colorectal cancer develops from the sequential acquisition of defined genetic mutations in the colonic epithelium. Tumorigenesis from normal tissue to cancer occurs largely through 3 pathways: the chromosomal instability pathway, the microsatellite instability pathway, and the sessile serrated pathway. Colorectal cancer incidence and mortality have decreased by approximately 35% since the beginning of screening programs in the 1990s, although other factors such as use of aspirin for coronary disease prevention and decreased smoking rates may also be important. In this review, we discuss the etiology, epidemiology, and histology of colorectal polyps and cancer.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.