Evidence map›Paper›PMID 35361148›Full record

ArticleBMC infectious diseases2022

Essential elements of and challenges to rapid ART implementation: a qualitative study of three programs in the United States.

Kimberly A Koester, Lissa Moran, Noelle LeTourneau, Lyndon VanderZanden, Susa Coffey, Pierre-Cedric Crouch, Janessa Broussard, John Schneider, Katerina A Christopoulos

Abstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kimberly A Koester *Department of Medicine, University of California, San Francisco, 550 16th Street, San Francisco, CA, USA. Kimberly.koester@ucsf.edu.
Lissa Moran *Department of Medicine, University of California, San Francisco, 550 16th Street, San Francisco, CA, USA.
Noelle LeTourneauDepartment of Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA.
Lyndon VanderZandenHoward Brown Health Center, 4025 N. Sheridan Rd, Chicago, IL, USA.
Susa CoffeyDepartment of Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA.
Pierre-Cedric CrouchSan Francisco AIDS Foundation, 470 Castro Street, San Francisco, CA, USA.
Janessa BroussardSan Francisco AIDS Foundation, 470 Castro Street, San Francisco, CA, USA.
John SchneiderHoward Brown Health Center, 4025 N. Sheridan Rd, Chicago, IL, USA.
Katerina A ChristopoulosDepartment of Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA.

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI ELBERT S. HUANG · 2011 to 2026
$10.0M
NIDDK NIH HHS P30 DK092949NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) initiation on the day of an HIV diagnosis or as soon as possible after diagnosis, known as rapid ART (henceforth "RAPID"), is considered to be a safe and effective intervention to quickly reduce viral load and potentially improve engagement in care over time. However, implementation of RAPID programming is not yet widespread. To facilitate broader dissemination of RAPID, we sought to understand health care worker experiences with RAPID implementation and to identify essential programmatic elements.

methodsWe conducted 27 key informant interviews with medical providers and staff involved in RAPID service delivery in three distinct clinical settings: an HIV clinic, a Federally Qualified Health Center and a sexual health and wellness clinic. Interviews were structured around domains associated with the Consolidated Framework for Implementation Research and were audio-recorded, transcribed, and thematically analyzed.

findingsWe identified seven (7) essential elements across settings associated with successful RAPID program implementation. These high-impact elements represent essential components without which a RAPID program could not function. There was no one requisite formation. Instead, we observed a constellation of essential elements that could be operationalized in various formations and by various people in various roles. The essential elements included: (1) presence of an implementation champion; (2) comfort and competence prescribing RAPID ART; (3) expedited access to ART medications; (4) expertise in benefits, linkage, and care navigation; (5) RAPID team member flexibility and organizations' adaptive capacity; (6) patient-centered approach; and (7) strong communication methods and culture.

conclusionsThe RAPID model can be applied to a diverse range of clinical contexts. The operational structure of RAPID programs is shaped by the clinical setting in which they function, and therefore the essential elements identified may not apply equally to all programs. Based on the seven essential elements described above we recommend future implementers identify where these elements currently exist within a practice; leverage them when possible; strengthen them when necessary or develop them if they do not yet exist; and look to these elements when challenges arise for potential solutions.

Indexed as

HIV InfectionsHealth FacilitiesHealth PersonnelHumansQualitative ResearchUnited StatesHIV treatmentImmediate ART qualitative methodsRapid ART

Identifiers

PMID35361148
PMCPMC8968260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.