Evidence map›Paper›PMID 35361139›Full record

ArticleBMC infectious diseases2022

Burden of respiratory syncytial virus-associated lower respiratory infections in children in Spain from 2012 to 2018.

Marco Heppe-Montero, Stefan Walter, Valentín Hernández-Barrera, Ruth Gil-Prieto, Ángel Gil-de-Miguel

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marco Heppe-MonteroDepartment of Preventive Medicine and Public Health, Rey Juan Carlos University, Alcorcón, Madrid, Spain. marcoheppe92@gmail.com.
Stefan WalterDepartment of Preventive Medicine and Public Health, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Valentín Hernández-BarreraDepartment of Preventive Medicine and Public Health, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Ruth Gil-PrietoDepartment of Preventive Medicine and Public Health, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Ángel Gil-de-MiguelDepartment of Preventive Medicine and Public Health, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Universidad Rey Juan Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infection (ALRI) leading to infant hospitalization, morbidity and postnatal mortality in children younger than 5 years of age worldwide. The aim of this study was to collect data on hospitalizations for RSV-related ALRI in children in Spain from 2012 to 2018.

methodsWe used the discharge reports from the Minimum Basic Data Set (MBDS) to retrospectively analyze hospital discharge data in children ≤ 14 years of age with a diagnosis of acute lower respiratory tract infection, based on the ICD-9-CM and ICD-10-CM diagnosis codes, from 2012 to 2018.

resultsA total of 190,474 children, 58.1% boys and 41.9% girls, were admitted for lower respiratory tract infections in Spain, including 118,731 cases of bronchiolitis, 53,972 cases of bronchitis, 3710 cases of RSV-positive pneumonia, and 14,061 cases of RSV infections. Of these, 92,426 children (48.5%) had laboratory-confirmed RSV infection. The mean case fatality rate was almost 6 times higher for pneumonia (0.6%) than for bronchiolitis (0.1%) or bronchitis (0.1%). A significant linear increase in the mean annual hospitalization rate for pneumonia of almost 15% per year was found, with no changes in the trend over the study period.

conclusionsRSV-related respiratory infections remain a leading cause of infant hospitalization in Spain. Effective antiviral treatments and preventive vaccines are urgently needed for the management of RSV infection in children, especially for those aged 6 to 12 months.

Indexed as

Pneumonia, ViralRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsChildFemaleHumansInfantMaleRetrospective StudiesSpainBronchiolitisBronchitisChildrenDisease burdenEpidemiologyHospitalizationPneumoniaRespiratory syncytial virusSpain

Identifiers

PMID35361139
PMCPMC8969337
OpenAlexW4220798339

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.