ArticleJoint diseases and related surgery2022
The effect of tranexamic acid on hidden blood loss in total hip arthroplasty.
Article in Joint diseases and related surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Efficacy and Safety of Combined Carbazochrome Sodium Sulfonate and Tranexamic Acid for Blood Loss Control in Patients Undergoing Total Hip Arthroplasty: A Systematic Review and Meta-Analysis.Iranian journal of medical sciences · 2026Pooled it
- Comparison between peri-articular injection and intra-articular injection of tranexamic acid during total knee arthroplasty: A meta-analysis.Joint diseases and related surgery · 2022Pooled it
- Analgesic effect of ropivacaine combined with methylene blue in fascia Iliaca block for patients undergoing hip arthroplasty.BMC musculoskeletal disorders · 2025Trial
- Association of oxidized regenerated cellulose powder and tranexamic acid during total knee arthroplasty: clinical outcomes.International orthopaedics · 2026Article
- Hidden blood loss estimation using perioperative hemoglobin drop: agreement with the Sehat formula.BMC surgery · 2026Article
- Hidden blood loss in total hip arthroplasty: A comparison of the direct anterior versus posterolateral approach.Joint diseases and related surgery · 2026Article
- Analysis of independent risk factors for high hidden blood loss following total knee arthroplasty.PloS one · 2026Article
- Effect of tranexamic acid on blood loss during THR in patients with inflammatory versus degenerative hip arthritis: A retrospective cohort study.Journal of clinical orthopaedics and trauma · 2025Article
- Article
- Hidden blood loss in unilateral open-door cervical laminoplasty for multilevel cervical spondylotic myelopathy.Joint diseases and related surgery · 2024Article
- Elastic Compression Dressing after Total Hip Replacement Slightly Reduces Leg Swelling: A Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Clinical Use of Tranexamic Acid in High Tibial Osteotomy: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2024Article
- A secure blood-saving protocol for Jehovah's Witnesses in primary total hip replacement.Joint diseases and related surgery · 2024Article
- Use of tranexamic acid may reduce the need for routine tourniquet use in total knee arthroplasty.Joint diseases and related surgery · 2022Article
- The hidden blood loss and its factors in patients undergoing minimally invasive knee arthroscopy.Frontiers in surgery · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIn this study, we aimed to examine the effect of tranexamic acid (TXA) on hidden blood loss in total hip arthroplasty (THA) patients. PATIENTS AND
methodsBetween June 2015 and June 2021, a total of 120 patients (45 males, 75 females; mean age 57.2±4.9 years; range, 45 to 67 years) with primary osteoarthritis who underwent THA without the use of TXA and 53 patients who received TXA were retrospectively analyzed. Demographic data, amount of transfusion, early complications, preoperative and postoperative hemoglobin and hematocrit values, total blood loss, visible blood loss, and hidden blood loss values were compared.
resultsThere was a significant difference between the groups with and without the use of TXA in terms of intraoperative bleeding, amount of blood in the drain, total blood loss, hidden blood loss, and blood transfusion (p<0.05). A significant positive correlation was found between intraoperative blood loss and hidden blood loss (r=0.325 p<0.01), while no significant correlation was found between postoperative drainage volume and hidden blood loss (r=-0.006 p=0.946).
conclusionThe use of TXA in patients undergoing THA reduces blood loss, including hidden blood loss, thereby reducing the need for blood transfusion after hip arthroplasty. However, there seems to be no linear relationship between postoperative blood loss and hidden blood loss. Considering these results, the routine use of TXA can be recommended in THA, unless there is a contraindication.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.