ArticleInternational journal of stroke : official journal of the International Stroke Society2023
Changes in physical activity and risk of ischemic stroke: The ARIC study.
Article in International journal of stroke : official journal of the International Stroke Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Associations of sleep duration, physical activity, and longitudinal changes with the risk of fatal stroke occurrence in middle-aged to older individuals : Physical activity, sleep duration, and risk of fatal stroke.BMC public health · 2026Article
- Article
- Sex disparities in the associations between accelerometer-measured movement behaviors and subsequent thromboembolism risk in cancer patients.Biology of sex differences · 2026Article
- Difference of onset rhythm in acute ischemic stroke patients with different TOAST subtypes.PloS one · 2026Article
- Objective physical activity characteristics and long-term functional disability trajectories in community-dwelling older adults: the amplifying risk of stroke.Frontiers in public health · 2026Article
- Combined associations of physical activity, diet quality and their trajectories with incidence of diabetes and cardiovascular diseases in the EPIC-Norfolk Study.Scientific reports · 2025Article
- Combined 25-hydroxyvitamin D concentrations and physical activity on mortality in US stroke survivors: findings from the NHANES.Nutrition journal · 2025Article
- Article
- Association of physical activity level and all-cause mortality among stroke survivors: evidence from NHANES 2007-2018.Environmental health and preventive medicine · 2025Article
- Association of triglyceride glucose index with clinical outcomes in ischemic stroke: a retrospective study.BMC neurology · 2024Observational
- Article
- Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011-2018 data.Frontiers in nutrition · 2024Article
- Trends in deaths and disability-adjusted life-years of stroke attributable to low physical activity worldwide, 1990-2019.BMC public health · 2023Article
- Physical Activity Over the Lifecourse and Cardiovascular Disease.Circulation research · 2023Review
- RDET stacking classifier: a novel machine learning based approach for stroke prediction using imbalance data.PeerJ. Computer science · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundLimited data exist regarding the impact of changes in physical activity (PA) over time on ischemic stroke risk. Exploring this understudied area could help improve stroke prevention strategies and promote PA during the lifespan.
methodsWe evaluated 11,089 Atherosclerosis Risk in Communities (ARIC) participants recruited in 1987-1989 who completed Visit 3 (1993-1995). We classified PA as meeting recommendations, not meeting recommendations, or no PA. Categories of increased, decreased, stable high, and stable low PA and a continuous PA variable were also evaluated. Crude and adjusted Cox regression models were used to characterize the association of 6-year changes in PA and ischemic stroke risk.
resultsParticipants had a mean age of 60 years. During a median of 21 years, 762 ischemic stroke events occurred. Compared to the participants with recommended PA at both visits, those with no PA had 46% higher hazards of ischemic stroke (hazard ratio (HR) = 1.46 (95% confidence interval (CI) = 1.17, 1.82)), and those with recommended PA at Visit 1 and no PA at Visit 3 also had 37% higher hazards (HR = 1.37 (95% CI = 1.02, 1.83)). Participants who increased their PA from Visit 1 to Visit 3 had 23% lower hazard than those with stable low PA at both visits (HR = 0.77 (95% CI = 0.63, 0.94)), while those who decreased their PA had 25% higher hazards compared to those with stable high PA at both visits (HR = 1.25 (95% CI = 1.01, 1.54)).
conclusionPhysical inactivity during midlife increases ischemic stroke risk, while meeting PA recommendations reduces it.
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Registered trials
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