Evidence map›Paper›PMID 35360948›Full record

SynthesisThe bone & joint journal2022

Curve type, flexibility, correction, and rotation are predictors of curve progression in patients with adolescent idiopathic scoliosis undergoing conservative treatment : a systematic review.

Lester P K Wong, Prudence W H Cheung, Jason P Y Cheung

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in The bone & joint journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Identifying predictors of brace treatment outcomes for adolescents or adults with idiopathic scoliosis: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  4. Can anterior vertebral body tethering provide superior range of motion outcomes compared to posterior spinal fusion in adolescent idiopathic scoliosis? A systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
  5. Article
  6. Comparison of brace treatment outcomes for patients with adolescent idiopathic scoliosis by degree of bone maturity: A study using the distal radius and ulna classification.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  8. Deletion of aJOR spine · 2026
    Article
  9. Does apical vertebra location influence the final outcome of bracing for idiopathic scoliosis?European journal of physical and rehabilitation medicine · 2026
    Observational
  10. Comprehensive scoliosis conservative rehabilitation for adolescent idiopathic scoliosis: effects on spinal deformity, physical function, and quality of life, with a parallel mediation analysis of core muscle endurance and pulmonary function.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lester P K WongDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.
Prudence W H CheungDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-3213-7373
Jason P Y CheungDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-7052-0875
University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of this study was to review the current evidence surrounding curve type and morphology on curve progression risk in adolescent idiopathic scoliosis (AIS).

methodsA comprehensive search was conducted by two independent reviewers on PubMed, Embase, Medline, and Web of Science to obtain all published information on morphological predictors of AIS progression. Search items included 'adolescent idiopathic scoliosis', 'progression', and 'imaging'. The inclusion and exclusion criteria were carefully defined. Risk of bias of studies was assessed with the Quality in Prognostic Studies tool, and level of evidence for each predictor was rated with the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. In all, 6,286 publications were identified with 3,598 being subjected to secondary scrutiny. Ultimately, 26 publications (25 datasets) were included in this review.

resultsFor unbraced patients, high and moderate evidence was found for Cobb angle and curve type as predictors, respectively. Initial Cobb angle > 25° and thoracic curves were predictive of curve progression. For braced patients, flexibility < 28% and limited in-brace correction were factors predictive of progression with high and moderate evidence, respectively. Thoracic curves, high apical vertebral rotation, large rib vertebra angle difference, small rib vertebra angle on the convex side, and low pelvic tilt had weak evidence as predictors of curve progression.

conclusionFor curve progression, strong and consistent evidence is found for Cobb angle, curve type, flexibility, and correction rate. Cobb angle > 25° and flexibility < 28% are found to be important thresholds to guide clinical prognostication. Despite the low evidence, apical vertebral rotation, rib morphology, and pelvic tilt may be promising factors. Cite this article:

Indexed as

KyphosisScoliosisAdolescentConservative TreatmentHumansRetrospective StudiesRotationAdolescent idiopathic scoliosisbone ageBracingCobb angleCorrectionCurve progressionFlexibilityMedlineMorphologypelvic tiltPrognostic Studiesrandomized controlled trialsRibRotationSystematic reviewthoracic kyphosisunivariate analysisvertebrae

Identifiers

PMID35360948
PMCPMC9020521
OpenAlexW4221072182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.