Evidence map›Paper›PMID 35360888›Full record

ArticleRSC chemical biology2022

Embedding a membrane protein into an enveloped artificial viral replica.

Hiroto Furukawa, Hiroshi Inaba, Yoshihiro Sasaki, Kazunari Akiyoshi, Kazunori Matsuura

Open access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hiroto FurukawaDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University Koyama-Minami 4-101 Tottori 680-8552 Japan ma2ra-k@tottori-u.ac.jp.
Hiroshi InabaDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University Koyama-Minami 4-101 Tottori 680-8552 Japan ma2ra-k@tottori-u.ac.jp.ORCID https://orcid.org/0000-0002-7658-7827
Yoshihiro SasakiDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University Katsura Nishikyo-ku Kyoto 615-8510 Japan.ORCID https://orcid.org/0000-0003-1333-5347
Kazunari AkiyoshiDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University Katsura Nishikyo-ku Kyoto 615-8510 Japan.
Kazunori MatsuuraDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University Koyama-Minami 4-101 Tottori 680-8552 Japan ma2ra-k@tottori-u.ac.jp.ORCID https://orcid.org/0000-0001-5472-7860
Tottori University · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural enveloped viruses, in which nucleocapsids are covered with lipid bilayers, contain membrane proteins on the outer surface that are involved in diverse functions, such as adhesion and infection of host cells. Previously, we constructed an enveloped artificial viral capsid through the complexation of cationic lipid bilayers onto an anionic artificial viral capsid self-assembled from β-annulus peptides. Here we demonstrate the embedding of the membrane protein Connexin-43 (Cx43), on the enveloped artificial viral capsid using a cell-free expression system. The expression of Cx43 in the presence of the enveloped artificial viral capsid was confirmed by western blot analysis. The embedding of Cx43 on the envelope was evaluated by detection

Identifiers

PMID35360888
PMCPMC8827153
OpenAlexW4200076693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.