Evidence map›Paper›PMID 35360858›Full record

ArticleFrontiers in genetics2022

Variants Within Genes

Gabrielle M Becker, Joan M Burke, Ronald M Lewis, James E Miller, James L M Morgan, Benjamin D Rosen, Curtis P Van Tassell, David R Notter, Brenda M Murdoch

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Gabrielle M BeckerDepartment of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, United States.
Joan M BurkeUSDA, ARS, Dale Bumpers Small Farms Research Center, Booneville, AR, United States.
Ronald M LewisDepartment of Animal Science, University of Nebraska-Lincoln, Lincoln, NE, United States.
James E MillerDepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
James L M MorganRound Mountain Consulting, Fayetteville, AR, United States.
Benjamin D RosenUSDA, ARS, Animal Genomics and Improvement Laboratory, Beltsville, MD, United States.
Curtis P Van TassellUSDA, ARS, Animal Genomics and Improvement Laboratory, Beltsville, MD, United States.
David R NotterDepartment of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA, United States.
Brenda M MurdochDepartment of Animal, Veterinary and Food Sciences, University of Idaho, Moscow, ID, United States.
Agricultural Research Service · USUniversity of Idaho · USDale Bumpers Small Farms Research Center · USLouisiana State University · USUniversity of Nebraska–Lincoln · USVirginia Tech · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal nematodes (GIN) pose a severe threat to sheep production worldwide. Anthelmintic drug resistance coupled with growing concern regarding potential environmental effects of drug use have demonstrated the necessity of implementing other methods of GIN control. The aim of this study was to test for genetic variants associated with resistance or susceptibility to GIN in Katahdin sheep to improve the current understanding of the genetic mechanisms responsible for host response to GIN. Linear regression and case-control genome-wide association studies were conducted with high-density genotype data and cube-root transformed weaning fecal egg counts (tFEC) of 583 Katahdin sheep. The case-control GWAS identified two significant SNPs (

Indexed as

gastrointestinal nematodesGWAShair sheephelminthparasites

Identifiers

PMID35360858
PMCPMC8960952
OpenAlexW4220909618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.