Evidence map›Paper›PMID 35360855›Full record

ArticleFrontiers in genetics2022

Profile and Functional Prediction of Plasma Exosome-Derived CircRNAs From Acute Ischemic Stroke Patients.

Jie Yang, Junli Hao, Yapeng Lin, Yijia Guo, Ke Liao, Min Yang, Hang Cheng, Ming Yang, Kejie Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
  8. Brain-Derived Exosomal CircRNAs in Plasma Serve as Diagnostic Biomarkers for Acute Ischemic Stroke.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie YangDepartment of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Junli HaoSchool of Bioscience and Technology, Chengdu Medical College, Chengdu, China.
Yapeng LinDepartment of Neurology, Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Yijia GuoInternational Clinical Research Center, Chengdu Medical College, Chengdu, China.
Ke LiaoInternational Clinical Research Center, Chengdu Medical College, Chengdu, China.
Min YangDepartment of Neurology, Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Hang ChengDepartment of Neurology, Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Ming YangDepartment of Neurology, Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Kejie ChenSchool of Public Health, Chengdu Medical College, Chengdu, China.
First Affiliated Hospital of Chengdu Medical College · CNChengdu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is one of the major causes of death and long-term disability, of which acute ischemic stroke (AIS) is the most common type. Although circular RNA (circRNA) expression profiles of AIS patients have been reported to be significantly altered in blood and peripheral blood mononuclear cells, the role of exosome-containing circRNAs after AIS is still unknown. Plasma exosomes from 10 AIS patients and 10 controls were isolated, and through microarray and bioinformatics analysis, the profile and putative function of circRNAs in the plasma exosomes were studied. A total of 198 circRNAs were differentially quantified (|log2 fold change| ≥ 1.00,

Indexed as

acute ischemic strokeceRNAcircRNAplasma exosomeprofile

Identifiers

PMID35360855
PMCPMC8963851
OpenAlexW4221122273

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.